The effect of olive or linseed oils supplemented with pure saturated fatty acids on serum cholesterol levels in the rat

• Autorzy: Hanczakowski P. , Szymczyk B.
• Języki publikacji: EN

Abstrakty

EN

A 6-week experiment on rats was performed to evaluate the growth-promoting and cholesterolaemic activity of olive and linseed oils mixed with pure myristic, palmitic or stearic acids. Each oil was mixed with each acid in a 1:1 w/w ratio. At the end of the experiment, blood was collected by cardiac puncture and total serum cholesterol (TC), HDL and LDL fractions, and serum triacylglycerols (TAG) were estimated. Mixing oils with pure fatty acids resulted in higher body weight gains. The longer the carbon chain of the acid, the higher were the body weight gains of the rats (1.99, 2.39 and 2.57 g per day for C14, C16 and C18, respectively). Myristic acid gave the highest level of TC (84.5 mg dl-1), while its mean content in pure fatty acids was only 77.34 mg dl-1. Myristic acid also accounted for the largest increase of TAG content in the case of both oils.

• Wydawca: -
• Czasopismo: Journal of Animal and Feed Sciences
• Rocznik: 2006
• Tom: 15
• Numer: 2
• Strony: 287-294
• Opis fizyczny: p.287-294,fig.,ref.

Twórcy

autor

Hanczakowski P.

• National Research Institute of Animal Production, 32-083 Balice, Poland

autor

Szymczyk B.

Bibliografia

• Allain C.C, Poon L.S., Chan C.S., Richmond W., Fu P.C., 1974. Enzymatic determination of total serum cholesterol. Clin. Chem. 20, 470-475
• Benz R., Suter P.M., 2004. Low HDL-cholesterol, high triglicerides – well known but often ignored. Schweiz Rundsch. Med. Prax. 93, 1911-1916
• Billet M.A., Bruce J.S., White D.A., Bennet A.J., Salter A.M., 2000. Interactive effects of dietary cholesterol and different saturated fatyy acids on liporotein metabolism in the hamster. Brit. J. Nutr. 84, 439-447
• Crespo N., Esteve-Garcia E., 2002. Nutrient and fatty acids deposition in broilers fed different dietary fatty acid profiles. Poultry Sci. 81, 1533-1542
• Dorfman S.E., Wang S., Vega-Lopez S., Jauhiainen M., Lichtenstein A.H., 2005. Dietary fatty acids and cholesterol differentially modulate HDL cholesterol metabolism in Golden-Syrian hamsters. J. Nutr. 135, 492-498
• Eggum B.O., 1973. A study of certain factors influencing protein utilization in rats and pigs. Beret. Forsoegslab. Statens. Husdyrbrugsudvalg. 406, 17-30
• Fernandez M.L., Soscia A.E., Sun G.S., Tosca M., McNamara D.J., McDonald B.E., 1996. Olive oil and rapeseed oil differ in their effect on plasma low-density liporotein metabolism in the guinea pig. Brit. J. Nutr. 76, 869-880
• Fernandez M.L., West K.L., Roy S., Ramjiganesh T., 2001. Dietary fat saturation and gender/ hormonal status modulate plasma lipids and lipoprotein composition. J. Nutr. Biochem. 12, 703-710
• Flickinger B.D., Huth P.J., 2004. Dietary fats and oils, technologies for improving cardiovascular health. Curr. Atheroscler. Rep. 6, 468-476
• Hanczakowski P., Szymczyk B., Szczurek W., 2004. The effect of pure saturated fatty acids on cholesterol and triacylglycerols level in rats. Ann. Anim. Sci. 4, 145-153
• Hegsted D.M., Mc Gandy R.B., Myers M.L., Stare F.J., 1965. Quantative effects of dietary fat on serum cholesterol in man. Amer. J. Clin. Nutr. 17, 281-295
• Javadi M., Everts H., Hovenier R., Kocsis S., Lankhorst A.E., Lemmens A.G., Schonewille J.T., Terpstra A.H., Beynen A.C., 2004. The effect of six different C18 fatty acids on body fat and energy metabolism in mice. Brit. J. Nutr. 92, 391-399
• Kris-Etherton P.M., 1993. Effects of chain length of saturated fatty acids on plasma total, LDL- and HDL-cholesterol levels. Fat Sci. Technol. 95, 448-452
• Kummerow F.A., Wasowicz E., Smith T., Yoss N.L., Thiel J., 1993. Plasma lipid physical properties in swine fed margarine or butter in relation to dietary magnesium intake. J. Amer. Coll. Nutr. 12, 125-132
• Mc Gowan M.W., Artiss J.D., Strandbergh D.R., Zak B., 1983. A peroxidase-coupled-method for the colorimetric determination of serum triglicerides. Clin. Chem. 29, 538-542
• Nagata J., Kasai M., Negishi S., Saito M., 2004. Effects of structured lipids containing eicosapentaenoic or docosahexoenoic acid and caprylic acid on serum and liver lipid profiles in rats. Biofactors 22, 157-160
• Nielsen L.B., Leth-Espensen P., Nordestgaard B.G., Foged E., Kjeldahl K., Stender S., 1995. Replacement of saturated dietary fat , effect on atherogenesis in cholesterol-fed rabbits clamped at the same plasma cholesterol level. Brit. J. Nutr. 74, 509-521
• Perona J.S., Canizares J., Montero E., Sanchez-Dominguez J.M., Ruiz-Gutierrez V., 2003. Plasma lipid modifications in elederly people after administration of two virgin olive oils of the same variety (Olea europea var. hojiblanca) with different triacylglycerol composition. Brit. J. Nutr. 89, 819-826
• Pronczuk A., Khosla P., Hayes K.C., 1994. Dietary myristic, palmitic and linoleic acid modulate cholesterolemia in gerbils. FASEB J. 8, 1191-1200
• Rajaram S., Burke K., Connel B., Muint T., Sabate J., 2001. A monounsaturated fatty acid –rich pecan-enriched diet favorably alters the serum lipid profile of healthy men and women. J. Nutr. 131, 2275-2279
• Sanz H., Lopez-Bote C.J., Menovo D., Bautista J.M., 2000. Abdominal fat deposition and fatty acid synthesis are lower and β-oxidation is higher in broiler chickens fed diets containing unsaturated rather than saturated fat. J. Nutr. 130, 3034-3037
• Trautwein E.A., Rieckhoff D., Kunath-Rau A., Erbersdobler H.F., 1999. Replacing saturated fat with PUFA-rich (sunflower oil) or MUFA-rich (rapeseed, olive and high-oleic sunflower oil) fats resulted in comparable hypocholesterolemic effects in cholesterol-fed hamsters. Ann. Nutr. Metabol. 43, 159-172
• Warrick G.R., Berdersond J., Alberts J.J., 1982. Dextran-sulphate-Mg precipitation procedure for quantitation of high-density lipoprotein cholesterol. Clin. Chem. 28, 1379-1388