Warianty tytułu
The comparison of sensibility to antibiotics of the lipophilic Corynebacterium sp. isolated from patients in the day of admission and during hospitalization
Języki publikacji
Abstrakty
Obecnie zakażenia szpitalne stanowią poważny problem zdrowotny, terapeutyczny i ekonomiczny ze względu na wzrost zakażeń z udziałem drobnoustrojów wieloopornych na antybiotyki. Oceniono częstość występowania lipofilnych gatunków Corynebacterium sp. izolowanych z próbek materiału pobranych od chorych w dniu przyjęcia do szpitala i podczas hospitalizacji oraz porównano wrażliwość na antybiotyki.
Lipophilic species of Corynebacterium are increasing problem in hospital infections. The aim of this study was to evaluate occurrence of these microorganisms in the materials taken from patients in the day of admission and during the hospitalization as well as comparison of their antibiotic sensitivity. The investigation included 65 strains isolated from hospitalized patients and 48 strains isolated from unchanged skin. Using Api Coryne test 5 species were identified. C. urealyticum dominated, the other were C. subsp. lipophilum and C. jeikeium. Among strains isolated from unchanged diseased skin the most C. jeikeium and C. accolens occured. All strains were sensitive to glicopeptide, quinupristin/dalphopristin. The strains isolated from hospitalized patients were usually sensitive to fuside acid, doxycycline as well as tetracycline. Strains isolated from unchanged skin were sensitive to almost all tested antibiotics. In the group of 65 strains isolated from hospitalized patients 99,0% were multiresistant. In the group of strains isolated from unchanged skin only two strains were multiresi- stant. Differences in antibiotic sensitivity among analysed Corynebacterium sp. were confirmed. Majority of the "hospital strains" were characterized by multiresistance. Basing on these results it is possible to suppose, that multiresistance is main factor that favours lipophilic Corynebacterium species in the process of colonization of mucous membranes, skins as well as developing infections.
Wydawca
Czasopismo
Rocznik
Tom
Numer
Strony
19-28
Opis fizyczny
s.19-28,rys.,bibliogr.
Twórcy
autor
- Collegium Medicum im. L.Rydygiera w Bydgoszczy Uniwersytetu Mikolaja Kopernika w Toruniu, ul.M.Sklodowskiej-Curie 9, 05-094 Bydgoszcz
autor
autor
Bibliografia
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- 6. Hryniewicz W, Subkowska A, Szczypa K i inni. Rekomendacje doboru testów do oznaczania wrażliwości bakterii na antybiotyki i chemioterapeutyki. Mikrobiol Med 2000, 2: 25-47.
- 7. Martinez-Martinez L, Ortego MC, Suárez AI. Comparison of E-test with broth microdilution and disk diffusion for susceptibility testing of coryneform bacteria. J Clin Microbiol 1995, 33: 1318- 21.
- 8. Mikucka A, Gospodarek E, Paprzycka M. Corynebacterium urealyticum w zakażeniach szpitalnych. Urol Pol 2000, 53: 188-98.
- 9. Mikucka A. Oportunistyczne gatunki coryneform w zakażeniach szpitalnych. Akademia Medyczna im. L. Rydygiera Bydgoszcz 2001. Praca doktorska.
- 10. NCCLS (National Comittee for Clinical Laboratory Standards). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobinally. Approved standard 6"' edition 2003, M7-A6 Wayne. PA.
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- 14. Riegel P, de brielD, PrčvostGi inni. Taxonomie study of Corynebacterium group ANF-1 strains: proposal of C. afermentans subsp. afermentans subsp. nov and C. afermentans subsp. Hpophilum sp. nov. Int J Syst Bacteriol 1993, 43: 287-92.
- 15. Riegel P, Ruimy R, de Briel D i inni. Genimic diversity and phylogenrtic relationships among lipid - requiring diphtheroids from humans and characterization of Corynebacterium macginleyi sp. nov. Jnt J Syst Bacteriol 1995, 45: 128-33.
- 16. Sekuta-Bauder D, Dworak-Stelmaska E, Kuklińska D. Przypadek bakteryjnego zapalenia wsierdzia (BZW) wywołanego przez Corynebacterium grupy JK. Przeg Epid 1995, 49: 395-7.
- 17. Sewell DL, Coyle MB, Funke G. Prosthetic valve endocarditis caused by Corynebacterium afermentans subsp. lipophilum (CDC coryneform group ANF-1). J Clin Microbiol 1995, 33: 759-61.
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
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