Cardiovascular and neurohormonal responses to lower body negative pressure [LBNP]: effect of training and 3 day bed rest

• Autorzy: Gasiorowska A. , Mikulski T. , Smorawinski J. , Kaciuba-Uscilko H. , Cybulski G. , Zieba A.W. , Krzeminski K. , Niewiadomski W. , Nazar K.
• Języki publikacji: EN

Abstrakty

EN

Both intensive training and bed confinement impair orthostatic tolerance, however, moderate training may exert beneficial effect on cardiovascular adjustment to gravitational stimuli. It was hypothesized that moderate training attenuates effects of bed rest. To test this assumption 24 healthy male volunteers aged 20.8±0.9 yrs were subjected to 6° head down bed rest (HDBR) for 3 days before and after 6 weeks of moderate endurance training. Before and after HDBR graded LBNP tests (-15, -30, -50 mmHg) were performed. During these tests heart rate (HR), stroke volume (SV), blood pressure (BP), plasma catecholamines, ACTH, adrenomedullin, atrial natriuretic peptide, plasma renin activity (PRA) and hematocrit were determined. HDBR did not systematically influence LBNP tolerance up to -50 mmHg, but it enhanced rates of reduction of SV, cardiac output and systolic BP and increased elevations of HR and PRA. Training did not alter significantly effects of HDBR on LBNP-induced changes in HR, SV, CO and TPR but it attenuated decrease in systolic BP and diminished increases in plasma noradrenaline and PRA. In conclusion, training has negligible effect on the HDBR-induced changes in central hemodynamics during LBNP but may increase vascular sensitivity to some vasoconstricting factors.

Słowa kluczowe

EN

cardiovascular response; neurohormonal response; lower body negative pressure; training; bed rest; head down bed rest; orthostatic tolerance; endurance training; hemodynamics; hormone

• Wydawca: -
• Czasopismo: Journal of Physiology and Pharmacology. Supplement
• Rocznik: 2006
• Tom: 57
• Numer: 10
• Strony: 85-100
• Opis fizyczny: p.85-100,fig.,ref.

Twórcy

autor

Gasiorowska A.

• Polish Academy of Sciences, 5 Pawinskiego Str., 02-106 Warsaw, Poland

autor

Mikulski T.

autor

Smorawinski J.

autor

Kaciuba-Uscilko H.

autor

Cybulski G.

autor

Zieba A.W.

autor

Krzeminski K.

autor

Niewiadomski W.

autor

Nazar K.