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2009 | 65 | 11 | 743-746
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Clostridium botulinum - charakterystyka i znaczenie epidemiologiczne

Autorzy
Warianty tytułu
EN
Clostridium botulinum - characteristic features and epidemiological significance
Języki publikacji
PL
Abstrakty
EN
Bacteria of the species Clostridium botulinum are sporeforming, gram-positive, anaerobic rods which are able to produce the most potent toxins in nature. Botulinum toxins are the etiologic factor of botulism in humans and animals. A lethal dose of botulinum toxin for a mouse is about 0.3 ng/kg, whilst a lethal dose for a human ranges from 0.2 µg/kg to 2 µg/kg. Historically, the differentiation of Clostridium botulinum strains is based on their ability to produce one of the seven botulinum toxins marked with letters from A to G. Nowadays, the classification based on the ability to produce botulinum toxins is not the only taxonomic criterion. C. botulinum strains are also divided into four groups which have different metabolic and culture features. Although, botulism is a rare disease, the outbreaks of botulism are difficult to control and cause economic losses in livestock. The species most susceptible to botulism are cattle and birds. The aim of this article is the characteristic of Clostridium botulinum, botulinum toxins, their action and botulism as a disease in some species of animals.
Wydawca
-
Rocznik
Tom
65
Numer
11
Strony
743-746
Opis fizyczny
s.743-746,bibliogr.
Twórcy
autor
  • Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy
autor
Bibliografia
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  • 6.Franciosa G., Ferreira J. L., Hatheway C. L.: Detection of type A, B, and E botulism neurotoxin genes in Clostridium botulinum and other Clostridium species by PCR: evidence of unexpected type B toxin genes in type toxigenic organisms. J. Clin. Microbiol. 1994, 32, 1911-1917.
  • 7.Hatheway C. L.: Botulism: The present status of the disease. Curr. Top Microbiol. Immunol. 1995, 195, 55-75.
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  • 14.Saed E. M. A.: Studies on Isolation and Identification of Clostridium botulinum Investigating Field Samples Specially from Equine Grass Sickness Cases. Praca dokt., Faculty of Agriculture, Goettingen University 2004.
  • 15.Sharma S. K., Whiting R. C.: Methods for of Clostridium botulinum Toxin in Foods. J. Food Prot. 2005, 68, 1256-1263.
  • 16.Simpson L. L.: The origin, structure, and pharmacological activity of botulinum toxin. Pharmacol. Rev. 1981, 33, 155-188.
  • 17.Smith L.: Botulism. The Organism, Its Toxins, The Disease. American lecture series, Springfield 1977, 3-15.
  • 18.Sobel J.: Botulism. Clin. Infect. Dis. 2005, 41, 1167-1173.
  • 19.Sperber W. H.: Requirements of Clostridium botulinum for growth and toxin production. Food Technol. 1982, 36, 89-94.
  • 20.Suen J. C., Hatheway C. L., Steigerwalt A. G., Brenner D. J.: Clostridium argentinense sp. Nov.: a genetically homogenous group composed of all strains of Clostridium botulinum toxin type G and some nontoxigenic strains previously identified as Clostridium subterminale or Clostridium hastiforme. Internat. J. System. Bacteriol. 1988, 38, 375-381.
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Typ dokumentu
Bibliografia
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Identyfikator YADDA
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