DNA repair of adriamycin induced damage in mouse and human cells differing in catalase activity

• Autorzy: Gruber B. M. , Anuszewska E.L.
• Języki publikacji: EN

Abstrakty

EN

Catalase is known to counteract cytotoxic effect of adriamycin, used as an anti-neoplastic drug. In cells with low catalase activity no repair of adriamycin induced lesions was observed up to 48 h post treatment. In cells with high catalase activity after 48 h the repair was either complete or partial depending on the human or mouse cell type used.

Słowa kluczowe

EN

mouse; cell; mice; human cell; DNA repair; adriamycin; catalase; cytotoxic effect

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 1998
• Tom: 45
• Numer: 2
• Opis fizyczny: p.573-577,fig.

Twórcy

autor

Gruber B. M.

• Drug Institute, Chelmska 30-34, 00-725 Warsaw, Poland

autor

Anuszewska E.L.

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