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2014 | 58 | 1 |
Tytuł artykułu

Expression of α and β oestrogen receptors within the claustrum in rabbit males

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The aim of the study was to investigate the presence of a (Erα) and ß (Erß) oestrogen receptors in rabbit male's claustrum, and thus to examine whether oestrogens may influence nerve cells' functions of this structure, llie material for the study was obtained from the brains of seven rabbits. To detect the presence of Erα and Erß, specific monoclonal antibodies were used. T"he expression of Erα and Erß was demonstrated in proper claustrum, as well as in the nucleus endopiriformis. For Erß, the reaction occurred mainly in the cell nucleus, whereas Erα was localised predominantly in the neuron cytoplasm. For both Erα and Erß, the nuclear and cytoplasmic localisation was observed in a small percentage of the examined cells. The obtained results may indicate oestrogen influence on the brain area and also suggest a further research on oestrogen-dependent pathways in males, which still remain greatly unexplored.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
58
Numer
1
Opis fizyczny
p.157-161,fig.,ref.
Twórcy
autor
  • Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin
autor
  • University Centre of Veterinary Medicine, Agricultural University of Cracow, 30-059 Cracow
autor
  • University Centre of Veterinary Medicine, Agricultural University of Cracow, 30-059 Cracow
autor
  • Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences, 20-950 Lublin
Bibliografia
  • 1. Białowąs J., Chadzypanagiotis D.: Structure of the claustrum in rabbits. Folia Morph 1972; 31, 73-80.
  • 2. Bodo C., Rissman E.: New roles for oestrogen receptor ß in behavior and neuroendocrinology. Front Neuroendocrinol 2006, 27, 217-232.
  • 3. Buchanan K.J., Johnson J.I.: Diversity of spatial relationships of the claustrum and insula in branches of the mammalian radiation. Ann NY Acad Sci 2011, 1225, 30-63.
  • 4. Caba M., Beyer C., Gonzalez Mariscal G., Morrell J.I.: Immunocytochemical detection of oestrogen receptor-alpha in the female rabbit forebrain: topography and regulation by estradiol. Neuroendocrinology 2003, 77, 208-222.
  • 5. Edelstein L.R., Denaro F.J.: The claustrum: a historical review of its anatomy, physiology, cytochemistry and functional significance. Cell Mol Biol 2004, 50, 675-702.
  • 6. Girgis K., Shin-Chang W.: Stereotaxic Atlas of the Rabbit Brain. Edited by W. H. Green, St. Louis, USA, 1981.
  • 7. Gooren L.J., Toorians A.W.: Significance of oestrogens in male (patho)physiology. Ann Endocrinol 2003, 64, 126-135.
  • 8. Kondarewicz A., Urban F., Marchlewicz M., Wiszniewska B.: Oestrogens in male reproductive system. Post Biol Kom 2008, 35, 499-516.
  • 9. Lehman M.N., Ebling F.J., Moenter S.M., Karsch F.J.: Distribution of oestrogen receptor- immunoreactive cells in the sheep brain. Endocrinology 1993, 133, 876-886.
  • 10. Lonc G.: Immunolocalisation of α and ß oestrogen receptors in basolateral amygdala of rabbit males. Bull Vet Inst Pulawy 2012, 56, 83-87.
  • 11. Majak K., Pikkarainen M., Kemppainen S., Jolkkonen E., Pitkanen A.: Projections from the amygdaloid complex to the claustrum and the endopiriform nucleus: a Phaseotus vulgaris leucoagglutinin study in the rat. J Comp Neurol 2002, 451, 236-249.
  • 12. McEwen B.S., Alves S.E.: Estrogen actions in the central nervous system. Endocrinol Rev 1999, 20, 279-307.
  • 13. Mitra S.W., Hoskin E., Yudkovitz J., Pear L., Wilkinson H.A., Hayashi S., Pfaff D.W., Ogawa S., Rohrer S.P., Schaeffer J.M., Mcewen B.S., Alves S.E.: Immunolocalization of estrogen receptor ß in the mouse brain: comparison with estrogen receptor α. Endocinology 2003, 144, 2055-2067.
  • 14. Nelson L.R., Bulun S.E.: Estrogen production and action J Am Acad Dermatol 2001, 45, 116-124.
  • 15. Österlund M.K., Hurd Y.L.: Estrogen receptors in the human forebrain and the relation to neuropsychiatrie disorders. Progr Neurobiol 2001, 64, 251-267.
  • 16. Paganini-Hill A., Henderson N.W.: Estrogen deficiency and risk of Alzheimer's disease in woman. Am J Epidemiol 1994, 140, 256-261.
  • 17. Perez S., Sendera T.J., Kordower J.H., Mufson E.J.: Estrogen receptor alpha containing neurons in the monkey forebrain: lack of association with calcium binding proteins and choline acetyltransferase. Brain Res 2004, 1019, 55-63.
  • 18. Shughrue P.J., Lane M.V., Merchenthaler I.: Comparative distribution of estrogen receptor-α and-ß mRNA in the rat central nervous system. J Comp Neurol 1997, 388, 507-525.
  • 19. Weiser M.J., Foradori Ch.D., Handa R.J.: Estrogen receptor beta in the brain: from form to function. Brain Res Rev 2008, 57, 309-320.
  • 20. Zhang J.Q., Cai W.Q., Zhou D.S., Su B.Y.: Distribution and differences of estrogen receptor ß immunoreactivity in the brain of adult male and female rats. Brain Res 2002, 935, 73-80.
  • 21. Zwain I.H., Yen S.S.: Neurosteroidogenesis in astrocytes, oligodendrocytes and neurons of cerebral cortex of rat brain. Endocrinology 1999, 140, 3843-52.
Typ dokumentu
Bibliografia
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Identyfikator YADDA
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