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Boguszewiecz, J. and Braszko, J. J.: The significance of Na⁺ ions in angiotensin II stimulation of acզuisition of active avoidance in rats. Acta physiol. pol., 1989, 40 (4): 409-412. Angiotensin II (1 μg) dissolved in water and given intracerebroventricularly on day 1, 15 min before the first learning session, enhanced rate of learning of active avoidance in rats over the next 7 days. However, the peptide, dissolved in 0.25 M NaCl, and given at the same dose and route,, stimulated learning significantly more than that dissolved in water. A possible involvement of Na⁺ ions in facilitating learning action of A II is discussed.
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p.409-412,fig.,ref.
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autor
- Chair and Department of Pharmacology, School of Medicine, Bialystok, Poland
autor
- Chair and Department of Pharmacology, School of Medicine, Bialystok, Poland
Bibliografia
- 1. Andersson, В., Jobin, M., Olson, K. (1967) A study of thirst and other effect of increased sodium concentration in the 3rd brain ventricle. Acta Physiol. Scand. 69. 29-36.
- 2. Andersson, В., Olson, K. (1973) Importance of sodium in central control of fluidhomeosthasis. In: Scow. Proc. 4th Int. Congr. Endocrinology, Wash.. 1973, p. 724. Excerpta Medica, Amsterdam.
- 3. Baranowska, D., Braszko, J. J., Wiśniewski, K. (1983) Effect of angiotensin II and vasopressin on acquisition and extinction of active avoidance in rats. Psychopharmacology 81. 247-251.
- 4. Braiszko, J. J. (1981) Physiological saline diminishes central behavioural stimulation produced by angiotensin II. J. Pharm. Pharmacol. 33. 192-193.
- 5. Braszko, J. J., Wiśniewski, K., Kupryszewski, G., Witczuk, B. (1987) Psychotropic effects of angiotensin II and III in rats: locomotor and exploratory vs cognitive behaviour. Behav. Brain Res. 25. 195-203
- 6. Yang, H. Y., Neff, N. H. (1972) Distribution and properties of angiotensin converting enzyme in rat brain. J. Neurochem. 19. 2443-2450.
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Bibliografia
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