Maximal oxygen uptake is associated with allele - 202 A of insulin - like growth factor binding protein - 3 (IGFBP3) promoter polymorphism and (CA)ntandem repeats of insulin - like growth factor IGF1 in Caucasians from Poland

• Autorzy: Gronek P. , Holdys J. , Krysciak J. , Wielinski D. , Slomski R.
• Języki publikacji: EN

Abstrakty

EN

 Physical fitness is a trait determined by multiple genes, and its genetic basis is modified by numerous environmental factors. The present study examines the effects of the (CA)n tandem repeats polymorphism in IGFI gene and SNP Alw21I restriction site -202 A>C polymorphism in IGF1BP3 on VO2max - a physiological index of aerobic capacity of high heritability. The study sample consisted of 239 (154 male and 85 female) students of the University School of Physical Education in Poznań and athletes practicing various sports, including members of the Polish national team. An association was found between -202 A/C polymorphism of IGFBP3 gene with VO2max in men. Higher VO2max values were attained by men with CC genotype, especially male athletes practicing endurance sports and sports featuring energy metabolism of aerobic/anaerobic character. A statistically significant influence of allele 188 and genotype 188/188 of tandem repeats (CA)n polymorphism of IGF1 gene on VO2max was found in women. Also, lower values of maximal oxygen uptake were noted in individuals with allele 186 or genotype 186/186, and higher VO2max values in athletes with allele 194.

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2014
• Tom: 61
• Numer: 2
• Opis fizyczny: p.245-252,ref.

Twórcy

autor

Gronek P.

• Department of Physiology, Faculty of Physical Education, Sport and Rehabilitation, The Eugeniusz Piasecki University School of Physical Education, Poznan, Poland

autor

Holdys J.

• Department of Physiology, Faculty of Physical Education, Sport and Rehabilitation, The Eugeniusz Piasecki University School of Physical Education, Poznan, Poland

autor

Krysciak J.

• Department of Physiology, Faculty of Physical Education, Sport and Rehabilitation, The Eugeniusz Piasecki University School of Physical Education, Poznan, Poland

autor

Wielinski D.

• Department of Anthropology and Biometrics, Faculty of Physical Education, Sport and Rehabilitation, The Eugeniusz Piasecki University School of Physical Education, Poznan, Poland

autor

Slomski R.

• Department of Anthropology and Biometrics, Faculty of Physical Education, Sport and Rehabilitation, The Eugeniusz Piasecki University School of Physical Education, Poznan, Poland

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