Occurrence of veterinary antibiotics and chemotherapeutics in fresh water, sediment, and fish of the rivers and lakes in Poland

• Autorzy: Gbylik-Sikorska M. , Posyniak A. , Mitrowska K. , Gajda A. , Bladek T. , Sniegocki T. , Zmudzki J.
• Języki publikacji: EN

Abstrakty

EN

The occurrence of commonly used veterinary antimicrobial agents was investigated in 159 fresh water, 443 fish, and 150 sediment samples from Polish rivers and lakes. The agents included aminoglycosides, ß-lactams, diaminopyrimidines, fluoroquinolones, lincosamides, macrolides, pleuromutilins, sulfonamides, and tetracyclines. The analysis was performed by three different sample preparation procedures for each matrix and it was performed by liquid chromatography-tandem mass spectrometry with electrospray ionisation source in positive mode, under the same conditions. All analy tical methods used were validated and showed good sensitivity , accuracy, and precision. The LOQ was in the range from 5 µg/kg to 125 µg/kg for fish samples, from 0.02 µg/L to 10 µg/L for fresh water samples, and from 1 µg/kg to 8 µg/kg for sediment samples.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2014
• Tom: 58
• Numer: 3
• Opis fizyczny: p.399-404,fig.,ref.

Twórcy

autor

Gbylik-Sikorska M.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Posyniak A.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Mitrowska K.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Gajda A.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Bladek T.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Sniegocki T.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Zmudzki J.

• Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland

Bibliografia

• 1. Borecka M., Białk-Bielinska A., Siedlewicz G., Kornowska K., Kumirska J., Stepnowski P., Pazdro K..: A new approach for the estimation of expanded uncertainty of results of an analytical method developed for determining antibiotics in seawater using solid-phase extraction disks and liquid chromatography coupled with tandem mass spectrometry technique. J Chromatogr A 2013, 1304, 138-146.
• 2. Chang X., Meyer M.T., Liu X., Zhao Q., Chen H., Chen J., Qiu Z., Yang L., Cao J., Shu W.: Deteremination of antibiotics in sewage form hospitals, nursery and slaughter house, wastewater treatment plant and source water Chongqing region of three Gorge Resorvoir in China. Environ Pollution 2010, 158, 1444-1450.
• 3. Commission Decision 2002/657/EC of August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Official Publications of the European Communities 2002, L 221, 8-36.
• 4. Gros M., Rodriguez-Mozaz S., Barcelo D.: Rapid analysis of multiclass antibiotics and some of their metabolites in hospital, urban wastewater and river water by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem mass spectrometry. J Chromatogr A 2013, 1292, 173-188.
• 5. Karthiheyan K.G., Meyer M.T.: Occurrence of antibiotics in wastewater treatment facilities in Wisconsin, USA. Sci Total Environ 2006, 361, 167-207.
• 6. Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J.: Multi-residue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography-positive electrospray ionisation tandem mass spectrometry. J Chromatogr A 2007, 1161, 132-145.
• 7. Kemper N.: Veterinary antibiotics in the aquatic and terrestrial environment. Eco Indie 2008, 8, 1-13.
• 8. Kim S.C., Carlson K.: Quantification of human and veterinary antibiotics in water and sediment using SPE/LC/MS/MS. Anal Bioanal Chem 2007, 387, 1301 -1315.
• 9. Kim Y., Jung J., Kim M., Park J., Boxall A.B.A., Choi K.: Prioritizing veterinary pharmaceuticals for aquatic environment in Korea. Environ Toxicol Pharmacol 2008, 26, 167-176.
• 10. Pena A., Paulo M., Silva L.J.G., Seifrtova M., Lino C.M., Solich P.: Tetracycline antibiotics in hospital and municipal wastewaters: a pilot study in Portugal. Anal Bioanal Chem 2010, 396, 2929-2936.
• 11. Romero-Gonzalez R., Lopez-Martinez J.C., Gomez-Milan E., Garrido-Frenich A., Martinez-Vidal J.L.: Simultaneous determination of selected veterinary antibiotics in gilthead seabream (Sparus aurata) by liquid chromatography-mass spectrometry. J Chromatogr B 2007, 857, 142-148.
• 12. Sacher F., Lange F.T., Brauch H.J., Blankenborn I.: Pharmaceuticals in groundwaters Analytical methods and results of a monitorin program in Baden-Wurttemberg, Germany. J Chromatogr A 2001, 938, 199-210.
• 13. Silvia M., Cruz D., Barcelo D.: LC-MS² trace analysis of antimicrobials in water, sediment and soil. Trend Anal Chem 2005, 24, 7.
• 14. Xuan Le T., Munekage Y.: Residues of selected antibiotics in water and mud from shrimp ponds in mangrove areas in Viet Nam. Marine Pollut Bull 2004, 49, 922-929.
• 15. Yang J.F., Ying G.G., Zhao J.L., Tao R., Su H.C., Chen F.: Simultaneous determination of four classes of antibiotics in sediments of the Pearl Rivers using RRLC-MS/MS. Sci Total Environ 2010, 408, 3424-3432.
• 16. Zhang R., Tang J., Li J., Cheng Z., Chaemfa C., Liu D., Zheng Q., Song M., Luo C., Zhang G.: Occurrence and risks of antibiotics in the coastal aquatic environment of the Yellow Sea, North China. Sci Total Environ 2013, 450-451, 197-204.
• 17. Zhou L.J., Ying G.G., Zhao J.L., Yang J.F., Wang L., Yang B., Liu S.: Trends in the occurrence of human and veterinary antibiotics in the sediments of the Yellow River, Hai River and Liao River in Northern China. Environ Pollut 2011, 159, 1877- 1885.

Identyfikatory

DOI

10.2478/bvip-2014-0062