Type 1 fimbriae in commensal Escherichia coli derived from healthy humans

• Autorzy: Pusz P. , Bok E. , Mazurek J. , Stosik M. , Baldy-Chudzik K.
• Języki publikacji: EN

Abstrakty

EN

 Type 1 fimbriae are one of the most important factors of Escherichia coli adaptation to different niches in the host. Our study indicated that the genetic marker - fimH gene occurred commonly in commensal E. coli derived from healthy humans but expression of the type 1 fimbriae was not observed. Identification of fim structural subunit genes (fimA-fimH) and recombinase fimE and fimB genes showed that many of the strains were carrying an incomplete set of genes and the genes expression study revealed that in strains with complete set of fim genes, the fimC gene, encoding the chaperone protein, was not expressed.

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2014
• Tom: 61
• Numer: 2
• Opis fizyczny: p.389-392,fig.,ref.

Twórcy

autor

Pusz P.

• Department of Biological Sciences, University of Zielona Gora, Poland

autor

Bok E.

• Department of Biological Sciences, University of Zielona Gora, Poland

autor

Mazurek J.

• Department of Biological Sciences, University of Zielona Gora, Poland

autor

Stosik M.

• Department of Biological Sciences, University of Zielona Gora, Poland

autor

Baldy-Chudzik K.

• Department of Biological Sciences, University of Zielona Gora, Poland

Bibliografia

• Baldy-Chudzik K, Niedbach J, Stosik M (2003) rep-PCR fingerptinting as a tool for the analysis of genomic diversity in Escherichia coli strains isolated from an aqueous/freshwater environment. Cell Mol Biol Lett 8: 793-798. 
• Blumer C, Kleefeld A, Lehnen D, Heintz M, Dobrindt U, Nagy G, Michaelis K, Emödy L, Polen T, Rachel R, Wendisch VF, Unden G (2005) Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli. Microbiology 151: 3287-3298. 
• Chapman TA, Wu XY, Barchia I, Bettelheim KA, Driesen S, Trott D, Wilson M, Chin JJ (2006) Comparison of virulence gene profiles of Escherichia coli strains isolated from healthy and diarrheic swine. Appl Environ Microbiol 72: 4782-4795. 
• Ewers C, Li G, Wilking H, Kiessling S, Alt K, Antáo EM, Laturnus C, Diehl I, Glodde S, Homeier T, Böhnke U, Steinrück H, Philipp HC, Wieler LH (2007) Avian pathogenic, uropathogenic, and newborn meningitis-causing Escherichia coli: how closely related are they? Int J Med Microbiol 297: 163-176. 
• Hernandes RT, Velsko I, Sampaio SC, Elias WP, Robins-Browne RM, Gomes TA, Girón JA (2011) Fimbrial adhesins produced by atypical enteropathogenic Escherichia coli strains. Appl Environ Microbiol 77: 8391-8399. 
• Iida KI, Mizunoe Y, Wai SN, Yoshida SI (2001) Type 1 fimbriation and its phase switching in diarrheagenic Escherichia coli strains. Clin Diagn Lab Immunol 8: 489-495. 
• Mitra A, Palaniyandi S, Herren CD, Zhu X, Mukhopadhyay S (2013) Pleiotropic roles of uvrY on biofilm formation, motility and virulence in uropathogenic Escherichia coli CFT073. PLoS One 8: e55492. 
• Nowrouzian FL, Friman V, Adlerberth I, Wold AE (2007) Reduced phase switch capacity and functional adhesin expression of type 1-fimbriated Escherichia coli from immunoglobulin a-deficient individuals. Infect Immun 75: 932-940. 
• Schwan WR (2011) Regulation of fim genes in uropathogenic Escherichia coli. World J Clin Infect Dis 1: 17-25.