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Eupatorium triplinerve Vahl belongs to the Asteraceae family, popularly known as Ayapana. It is a perennial shrub native to Amazon rainforests of South America. Its leaves are used through infusions, decoctions, baths, and tea. It is largely used in Brazilian folk medicine as sedative, febrifuge, stimulant, tonic and anti-inflammatory. The essential oil from aerial parts of Eupatorium triplinerve was analysis by gas chromatography mass spectroscopy (GC-MS). Thirty compounds representing 98.24 % of the oil were identified. The major compounds were 2-tert-butyl-1,4-methoxybenzene (74.3 %) and b-Selinene (8.6 %). The antibacterial activity of the essential oil was evaluated against ten bacteria (including Gram positive and Gram negative) and six phytopathogenic fungi. The oil exhibited moderated antibacterial and strong antifungal activity against all the test pathogens. The highest zone inhibition was recorded against Salamella typhae (21 mm) followed by Shigella sonnei (18 mm) at a concentration of 20μl/ disc on the other standard Ampicillin 20mg/ disc showed on average of 14-34 mm diameter of zone inhibition against the test organism. The lowest antifungal activities were recorded against Macrophomina phaseoline, and Botryodiplodia theobromae. The highest Alternaria alternate (12000 ppm). Further pharmacological and toxicology studies will be required to establish the therapeutic uses of this oil.
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p.14-21,ref.
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- Department of Botany, Annamalai University, Annamalai Ngar 608 002, Tamil Nadu, India
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- Department of Botany, Annamalai University, Annamalai Ngar 608 002, Tamil Nadu, India
autor
- Department of Botany, Annamalai University, Annamalai Ngar 608 002, Tamil Nadu, India
Bibliografia
- [1] Ahmed, A.M.A., M.S. Rahman and M.N. Anwar. 2002. Antimicrobial activity of extracts and crude alkaloids isolated from the leaf of Adhatoda vasica Nees. Bangladesh J. Life Sci. 15(2), 125-128.
- [2] Canales-Martinez, M., Hernandez-Delgado, T., Flores Ortiz, C., Duran Diaz, A. 2005. Antimicrobial Activity of Alternant era caracasana. Pharmaceutical Biology, 43(4): 305-307
- [3] Ghani, A. 1998. Medicinal plants of Bangladesh: Chemical constituents and uses. 1st edn. Asiatic Society of Bangladesh. pp. 174.
- [4] Garg, S.C. and Nakhare, S. 1993. Studies on the essential oil from the flower of Eupatorium triplinerve. Ind. Perfum. 37: 318-323.
- [5] Garg, S.C. and Nigam, S.S. 1970. Chemical examination of the essential oil from the leaves of Eupatorium triplinerve. Flav. Ind. 1: 469-472.
- [6] Ghani, A. 2003. Medicinal Plants of Bangladesh with Chemical constituents and Uses. 2nd edn. Asiati Society of Bangladesh, pp. 224-225.
- [7] Gupta, D., Charle, R. and Garg, S. N. 2004.Chemical composition of the essential oil from the leaves of Eupatorium triplinerve Vahl. J. Essentl. Oil Res. 16(5): 473-475
- [8] Jones, N.R., Barry, L.A., Gavan, L.T. and Washington II, J.A. 1985. Susceptibility tests: Microdilution and macrodilution broth procedures.In manual of clinical microbiology (Lennette EH, bellows A, Hausler Jr. W.J and Shadomy HJ eds.) 4th edn. American society of microbiology, Washington DC, pp. 972-976.
- [9] Kokate, C., and Verma, K.C. 1971. Pharmacological studies on the essential oil of Eupatorium triplinerve. Flavour Ind. 2(3): 177-180.
- [10] Sharma, S.K. and Singh, V.P. 1979. The antifungal activity of some essential oils. Indian Drugs Pharm Ind. 14(1): 3-6.
- [11] Yadava, R.N. and Saini, V.K. 1980. In vitro Anti microbial efficacy of the essential oil of Eupatorium triplinerve leaves. Ind. Perfum. 34(1): 61-63.
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Bibliografia
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