Warianty tytułu
Języki publikacji
Abstrakty
We report on preparation of poly(acrylic acid-co-methyl methacrylate) (PAM) micro- and nanoparticles and, in the subsequent stage, complexation reaction with the active substance - metronidazole (MET). The drug release behavior of MET - loaded PAM micro- and nanoparticles was evaluated in water and phosphate buffered saline (PBS, 0.9% NaCl) at 37ºC. It has been found that introduction of MET into PAM micro- and nanoparticles enabled gradual and controlled release of the active substance. Structural analysis using FT-IR (ATR) and 1H NMR, as well as surface morphology assessment by SEM, were performed.
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Opis fizyczny
p.835-838,fig.,ref.
Twórcy
autor
- Department of Chemistry and Technology of Polymers, Cracow University of Technology, Krakow, Poland
autor
- Department of Chemistry and Technology of Polymers, Cracow University of Technology, Krakow, Poland
Bibliografia
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Typ dokumentu
Bibliografia
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Identyfikator YADDA
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