Assessment of CD11b and CD11/18 integrin expression on leukocytes of dogs with atopic dermatitis

• Autorzy: Taszkun I.
• Języki publikacji: EN

Abstrakty

EN

Cytometric analysis was performed in order to detect the expression of surface molecules CD11b and CD11/18 on lymphocytes, granulocytes, and monocytes of peripheral blood of dogs with atopic dermatitis (AD) complicated by purulent dermatitis. The percentage of peripheral blood lymphocytes with CD11b and CD11/18 was found to be significantly higher (P < 0.05) in dogs with AD than in healthy dogs. The percentage of granulocytes expressing CD11b molecule was significantly lower in dogs with complicated AD compared to healthy dogs and dogs with uncomplicated AD. The expression of CD11b and CD 11/18 integrin on monocytes of dogs with complicated AD depended on the severity of symptoms and was higher in dogs with deep purulent dermatitis. It was concluded that the expression of CD11b and CD11/18 integrin on leukocytes of dogs with AD depends on the stage of the disease.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2014
• Tom: 58
• Numer: 1
• Opis fizyczny: p.99-103,fig.,ref.

Twórcy

autor

Taszkun I.

• Sub-Department of Clinical Diagnostics and Veterinary Dermatology, Department and Clinic of Internal Medicine, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20–612 Lublin, Poland,

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