Results of Surgical Treatment of Colorectal Cancer in Octogenerians Patients

• Autorzy: Wiesław Tarnowski , Piotr Kamiński , Krzysztof Bielecki
• Języki publikacji: EN

Abstrakty

EN

The aim of the study was to estimate factors affecting results of surgical treatment of colorectal cancer in octogenarian patients in comparison with a group of younger patients.Material and methods. Hospital records were reviewed prospectively and data were collected from a consecutive series of 1021 patients operated on because of primary colorectal cancer between 1988 and 2009.Results. One hundred sixteen patients aged minimum 80 years of life were identified with an average age of 83.6 years. They were compared with 905 younger patients with an average age of 61.9 years. Co-morbidity, presentation in ASA 2, ASA 3 and ASA 4 score were significantly higher in octogenarian than in younger patients group. Emergent operations were performed significantly more often in octogenerians than in younger patients as well (31% versus 14% respectively). Resection of cancer and primary bowel anastomosis was performed less often in patients aged over 80 years than in younger patients (58.6% versus 70.9% respectively). Postoperative complications rate was significantly higher among the older than younger patients (43.9% versus 30.7% respectively). Mortality was higher in older than in younger patients (22.4% vs 5.7% respectively).Conclusions. Results of surgical treatment of colorectal cancer in octogenarian patients are affected by higher co-morbidity and more often presentation of ASA 3 and ASA 4 score than in younger patients. Surgical treatment of colorectal cancer in octogenarians is burdened with higher rate of postoperative complications and almost four times higher mortality rate than in younger patients.

Słowa kluczowe

EN

octogenarian patients; colorectal cancer; post-operative complications

• Wydawca: Index Copernicus International
• Czasopismo: Polish Journal of Surgery
• Rocznik: 2010
• Tom: 82
• Numer: 7
• Strony: 410-416

Daty

wydano

2010-07-01

online

2010-10-22

Twórcy

autor

Wiesław Tarnowski

• Department of General and Digestive Tract Surgery, Postgraduate Medical Education Center in Warsaw

autor

Piotr Kamiński

• Department of General and Digestive Tract Surgery, Postgraduate Medical Education Center in Warsaw

autor

Krzysztof Bielecki

• Department of General and Digestive Tract Surgery, Postgraduate Medical Education Center in Warsaw

Bibliografia

• Wronkowski Z, Zwierko M. Epidemiologia, czynniki ryzyka i możliwości zapobiegania. W: Nowacki M - Nowotwory jelita grubego. Wydawnictwo Wiedza i Życie; Warszawa 1996; str. 24-50.
• Smith JJ, Lee J, Burke C et al.: Major colorectal cancer resection should not be denied to the elderly. EJSO 2002; 28: 661-66.
• Stan i struktura ludności. Ludność według płci i wieku w 2006 roku. Rocznik Demograficzny 2007; Strona 120-121. Osiągnięto z:
• Krasnodębski IW, Kopeć D: Rak jelita grubego powyżej 80 roku życia - możliwości i wyniki leczenia. Proktologia 2001; 2: 21-32.
• Isbister WH: Colorectal surgery in the elderly: an audit of surgery in octogenerians. ANZJ Surg 1997; 67: 557-61.
• Fitzgerald SD, Longo WE, Daniel G et al.: Advanced colorectal neoplasia in the high-risk elderly patient: is surgical resection justified? Dis Colon Rectum 1993; 36: 161-66.
• Ong ES, Alassas M, Dunn KB et al.: Colorectal cancer surgery in the elderly: acceptable morbidity? Am J Surg 2008; 195: 344-48.
• Kirchgatterer A, Steiner P, Hubner D et al.: Colorectal cancer in geriatric patients: Endoscopic diagnosis and surgical treatment. World J Gastroenterol 2005; 11: 315-18.
• Sunouchi K, Namiki K, Mori M et al.: How should patients 80 years of age or older with colorectal carcinoma be treated? Long-term and short-term outcome and postoperative cytokine levels. Dis Colon Rectum 2000; 43: 233-41.
• Fabre J.M, Rouanet P, Ele N et al.: Colorectal carcinoma in patients aged 75 years and more: factors influencing short and long term operative mortality. Int Surg 1993; 78: 200 - 203.
• Coburn MC, Pricolo VE, Soderberg CH: Factors affecting prognosis and management of carcinoma of the colon and rectum in patients more than eighty years of age. J Am Coll Surg 1994; 179: 65-69.
• Marusch F, Koch A, Schmidt U et al.: The impact of the risk factor "Age" on the early postoperative results of surgery for colorectal carcinoma and its significance for perioperative management. World J Surg 2005; 29: 1013-22.
• Kemppainen M, Räihä I, Rajala T et al.: Characteristics of colorectal cancer in elderly patients. Gerontology 1993; 39: 222-27.
• Spivak H, Maele DV, Friedman I et al.: Colorectal surgery in octogenerians. J Am Coll Surg 1996; 183: 46-50.
• Mäkelä JT, Kiviniemi H, Laitinen S: Survival after operations for colorectal cancer in patients aged 75 years or over. Eur J Surg 2000; 166: 473-79.
• Lee L, Jannapureddy M, Albo D et al.: Outcomes of Veterans Affairs patients older than age 80 after surgical procedures for colon malignancies. Am J Surg 2007; 194: 646-51.
• Tsugawa K, Koyanagi N, Hashizume M et al.: Therapeutic strategy of emergency surgery for colon cancer in 71 patients over 70 years of age in Japan. Hepato-gastroenterology 2002; 49: 393-98.
• Agarwal N, Leighton L, Mandile MA et al.: Outcomes of surgery for colorectal cancer in patients age 80 years and older. Am J Gastroenterol 1990; 85: 1096-1101.
• Hardiman KM, Cone M, Sheppard BC et al.: Disparities in the treatment of colon cancer in octogenerians. Am J Surg 2009; 197: 624-28.
• Chautard J, Alves A, Zalinski S et al.: Laparoscopic colorectal surgery in elderly patients: a matched case-control study in 178 patients. J Am Coll Surg 2008; 206: 255-60.
• Vignali A, Di Palo S, Tamburini A et al.: Laparoscopic vs. Open colectomies in octogenerians: a case-matched control study. Dis Colon Rectum 2005; 48: 2070-75.

Identyfikatory

DOI

10.2478/v10035-010-0057-2