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2012 | 18 | 1 | 11-21
Tytuł artykułu

Establishment of in vitro 192Ir γ-ray dose-response relationship for dose assessment by the lymphocyte dicentric assay

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
In vitro dose-response relationships are used to describe the relation between dicentric chromosomes and radiation dose for human peripheral blood lymphocytes. The dicentric yield depends on both the dose and the radiation quality. Thus, for reliable dose estimation in vitro dose responses must be determined for different radiation qualities. This paper reports the work for setting up the relationship for the dicentric production in the lymphocytes exposed in vitro to 192Ir g-rays at Central Laboratory for Radiological Protection (CLOR). In a case of a radiation accident in industrial radiography using 192Ir sealed sources, this will be the basis for the indirect evaluation of the g-ray dose to which an accidental victim was exposed.
Wydawca

Rocznik
Tom
18
Numer
1
Strony
11-21
Opis fizyczny
Daty
wydano
2012-03-01
online
2013-02-26
Twórcy
  • Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland, kowalska@clor.waw.pl
  • Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland
  • Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland
Bibliografia
  • [1] Bauchinger M (1983). Microdosimetric aspects of the induction of chromosome aberrations. In: Ishihara T and Sasaki MS (eds) Radiation induced chromosome damage in man. New York: Alan R Liss, Inc, 1-22
  • [2] Bender MA and Gooch PC (1962). Persistent chromosome aberrations in irradiated human subjects. Radiat Res, 16, 44-53.
  • [3] Bilski P (2001). Dosimetric properties of an LiF:Mg,Cu,P thermoluminofor. Ph.D. thesis, Krakow, IFJ.
  • [4] Deperas J, Szłuińska M, Deperas-Kamińska M, Edwards A, Lloyd D, Lindholm C, Romm H, Roy L, Moss R, Morand J, Wojcik A (2007). CABAS - a freely available PC program for fitting calibration curves in chromosome aberration dosimetry. Radiat Prot Dosim, 124, 115-123.[Crossref][WoS]
  • [5] Edwards AA, Lloyd DC and Purrott RC (1979). Radiation-induced chromosome aberrations and the Poisson distribution. Radiat Environ Biophys,16, 89-100.[Crossref][PubMed]
  • [6] IAEA. (1986). Biological dosimetry: Chromosomal aberration analysis for dose assessment. Technical Reports 260. (Vienna: International Atomic Energy Agency).
  • [7] IAEA. (2001). Cytogenetic analysis for radiation dose assessment. A Manual. Technical Report 405. (Vienna: International Atomic Energy Agency).
  • [8] ICRU. (1980). Linear Energy Transfer. Report 6. Washington DC. International Commission on Radiological Units.
  • [9] Kellerer AM and Rossi HH (1972). The theory of dual radiation action. Curr Top Radiat Res Q, 8, 85-158.
  • [10]Papworth DG (1975). Curve fitting by maximum likelihood. Appendix to paper by JRK Savage, Radiation induced chromosomal aberrations in the plant Trasdescantia. Dose-response curves. Radiat. Botanic, 15, 87.
  • [11]Savage JRK and Papworth DG. (2000). Constructing a 2B calibration curve for retrospective dose reconstruction. Radiat. Prot. Dosim, 88, 69-76.
  • [12]Sevan’kaev AV, Lloyd DC, Edwards AA, Moquet JE, Nugis VYu, Mikhailova GM, Potetnaya OI, Khvostunov IK, Guskova AK, Baranow AE and Nadejina NM (2002). Cytogenic investigations of serious overexposure to industrial gamma radiography source. Radiat. Prot. Dosim, 102, 201-206.
  • [13]Sreedevi B., Rao BS and Bhatt B. (1993). Radiation-induced chromosome aberration yields following an accidental non-uniform exposure. Radiat. Prot. Dosim, 50, 45-49.
  • [14]Szłuińska M, Edwards D, Lloyd D (2007). Presenting statistical uncertainty on cytogenetic dose estimates. Radiat. Prot. Dosim, 123, 443-449.[WoS]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_v10013-012-0003-1
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