Hydatidiform mole mimicking an enlarged uterine fibromyoma four months after ART

• Autorzy: Milan Terzic , Jelena Dotlic , Sanja Maricic , Ivana Babovic
• Języki publikacji: EN

Abstrakty

EN

Hydatidiform mole is a pregnancy disorder, of a benign nature. We present a case of molar tissue within a uterine myoma, the first such entity reported in the literature. In May 2006, a thirty-eight year old infertility patient was admitted for myomectomy. She had anamnesis for chronic pelvic inflammatory disease and surgeries performed for tubal pregnancies. After the sixth intracytoplasmal spermatozoa injection procedure performed in January 2006, she conceived, but curettage was performed in March 2006 for a missed abortion. Following the routine preoperative evaluation in May 2006, four months after the last artificial reproductive technology procedure, myomectomy was performed as uneventful operation, but the histological report appeared unusual, showing degenerated chorionic villi within the uterine myoma. Molar tissue within uterine myoma might evolve even after artificial reproductive procedures. Furthermore, this finding might be misinterpreted as a fibromyoma degeneration. This is the first, and a unique case, of molar tissue within uterine myoma reported in the literature.

Słowa kluczowe

EN

Hydatiform mole; Infertility; Uterine myoma; ART; Surgery

• Czasopismo: Open Medicine
• Rocznik: 2011
• Tom: 6
• Numer: 2
• Strony: 201-204

Daty

wydano

2011-04-01

online

2011-02-17

Twórcy

autor

Milan Terzic,

autor

Jelena Dotlic

• Institute of Gyn/Obs Clinical Centar of Serbia, 11000, Belgrade, Serbia

autor

Sanja Maricic

• General Health Center “Savski Venac”, 11000, Belgrade, Serbia

autor

Ivana Babovic

• Institute of Gyn/Obs Clinical Centar of Serbia, 11000, Belgrade, Serbia

Bibliografia

• [1] Garner E.I., Goldstein D.P., Feltmate C.M, Berkowitz R.S. Gestational trophoblastic diseases. Clin Obstet Gynecol 2007, 50, 112–122 http://dx.doi.org/10.1097/GRF.0b013e31802f17fc[Crossref]
• [2] Horn L.C., Kowalzik J., Bilen K., Richter C.E., Einenkel J. Clinicopathological characteristics and subsequent pregnancy outcome in 139 complete hydatiformole. Eur J Obstet Gynecol Reprod Biol 2006, 128, 10–14 http://dx.doi.org/10.1016/j.ejogrb.2006.01.024[Crossref]
• [3] Bhatia K., Bentick B. Intramural molar pregnancy: a case report. J Reprod Med 2004, 49, 689–692
• [4] Martaadisoebrata D. Invasive mole: Indonesian perspective. J Reprod Med 2007, 52, 839–842 [PubMed]
• [5] Juanquing L., Yifu S., Xiaoyun W., Weimiao Y., Caiyun Z., Honglang Q. Intratumoral Blood Flow Analysis in Epitheloid Trophoblastic Tumors. J Ultrasound Med 2009, 28, 1709–1714
• [6] Altman A.D., Bentley B, Murray S., Bentley J.R. Maternal age-related rates of gestational trophoblastic disease. Obstet Gynecol 2008, 112, 244–250 http://dx.doi.org/10.1097/AOG.0b013e3181802186[Crossref]
• [7] Wells M. The pathology of gestational trophoblastic disease: recent advances. Pathology 2007, 39, 88–96 http://dx.doi.org/10.1080/00313020601137367[Crossref]
• [8] Mangili G., Garavaglia E., Cavoretto. P., Gentile C., Scarfone G., Rabiaotti E. Clinical presentation of hydatidiform mole in northern Italy: has it changed in the last 20 years? Am J Obstet Gynecol 2008, 198, 302–314 http://dx.doi.org/10.1016/j.ajog.2007.09.036[Crossref][WoS]
• [9] Chauhan M.B., Chaudhary P., Dahiya P., Sangwan K., Sen J. Molar cornual ectopic pregnancy. Acta Obstet Gynecol Scand 2006, 85, 625–627 http://dx.doi.org/10.1080/00016340600604302[Crossref]
• [10] Sebire N.J., Lindsay I., Fisher R.A., Savage P., et al. Overdiagnosis of complete and partial hydatidiform mole in tubal ectopic pregnancies. Int J Gynecol Pathol 2005, 24, 260–264 http://dx.doi.org/10.1097/01.pgp.0000164597.19346.b5[Crossref]
• [11] Mao T., L, Kurman R.J., Huang C.C., Li M.C., Shih Ie.M. Immunohistochemistry of choriocarcinoma:an aid in differential diagnosis and in elucidating pathogenesis. Am J Surg Pathol 2007, 31, 1726–1732 http://dx.doi.org/10.1097/PAS.0b013e318058a529[WoS][Crossref]
• [12] Niemann I., Bolund L., Sunde L. Twin pregnancies with diploid hydatidiform mole and co-existing normal fetus may originate from one oocyte. Hum Reprod 2008, 23, 2031–2035 http://dx.doi.org/10.1093/humrep/den226[WoS][Crossref]
• [13] Vandenhove M., Amant F., Van Schoubroeck D., Cannie M., Dymarkowski S. Complete hydatidiform mole with co-existing healthy fetus: a case report. J Matern Fetal Neonatal Med 2008, 21, 341–344 http://dx.doi.org/10.1080/14767050801925156[Crossref][WoS]
• [14] Dedes I., Christodoulou E., Ziogas V. Complete hydatidiform mole coexisting with a viable pregnancy as twins after intracytoplasmic sperm injection: a case report. J Reprod Med 2008, 53, 227–230
• [15] Montes-de-Oca-Valero F., Macara L., Shaker A. Twin pregnancy with a complete hydatidiform mole and co-existing fetus following in-vitro fertilization: case report. Hum Reprod 1999, 14, 2905–2907 http://dx.doi.org/10.1093/humrep/14.11.2905[Crossref]

Identyfikatory

DOI

10.2478/s11536-010-0077-7