Molecular characterization of rotaviruses in mid-western Turkey, 2006–2007

• Autorzy: Mustafa Altindis , Krisztián Bányai , Raike Kalayci , Cihangir Gulamber , Resit Koken , Teoman Apan , Esra Koçoğlu , Aysegul Bukulmez , Yasin Yoldas , Pınar Aykurt
• Języki publikacji: EN

Abstrakty

EN

Vaccines against rotaviruses are now available in numerous countries, including Turkey. As the vaccines may show various efficiencies against different type specificities and routine vaccination in infants might result in selection and immune escape of wild-type rotavirus strains, strain surveillance has been initiated before and during the vaccine introduction. We aimed to provide corresponding information on local strain prevalence in Anatolia, mid-western Turkey during the introduction of rotavirus vaccines. Stool samples positive for group A rotavirus by commercial enzyme immunoassay were subjected to reverse transcription-polymerase chain reaction based genotyping of the outer capsid antigens, VP7 and VP4, determining G and P type specificities respectively. Among 36 fully and 5 partially typeable strains we detected genotype G1, G2, and G9 VP7 specificities and genotype P[4], P[6] and P[8] VP4 specificities in 5 individual and 4 mixed combinations. The most common strain was G2P[4] (n=17), followed by G9P[8] (n=9). Other strains were G1P[8] (n=2), G2P[8] (n=2), G1+2P[8] (n=2), G9P[4] (n=1), G2+9P[8] (n=1), G4+9P[6] (n=1), and G2P[4+8] (n=1). Partially typed strains included 2 G1P[NT] and 3 G2P[NT] strains. Our data may help determine a baseline of the rotavirus genotype prevalence in Turkey and see if changes in the incidence of individual strains will be observed after routine use of vaccine.

Słowa kluczowe

EN

Rotavirus; Genotyping; VP7; VP4; Reassortment; Vaccine

• Czasopismo: Open Medicine
• Rocznik: 2010
• Tom: 5
• Numer: 5
• Strony: 640-645

Daty

wydano

2010-10-01

online

2010-08-20

Twórcy

autor

Mustafa Altindis

• Department of Microbiology, Afyon Kocatepe Üniversity School of Medicine, 03200, Afyonkarahisar, Turkey,

autor

Krisztián Bányai

• Veterinary Medical Research Institute, Hungarian Academy of Sciences, H-1143, Budapest, Hungary

autor

Raike Kalayci

• Department of Microbiology, Afyon Kocatepe Üniversity School of Medicine, 03200, Afyonkarahisar, Turkey

autor

Cihangir Gulamber

• Department of Microbiology, Afyon Kocatepe Üniversity School of Medicine, 03200, Afyonkarahisar, Turkey

autor

Resit Koken

• Department of Pediatrics, Afyon Kocatepe Üniversity School of Medicine, 03200, Afyonkarahisar, Turkey

autor

Teoman Apan

• Department of Microbiology, Kirikkale University, School of Medicine, 71100, Kirikkale, Turkey

autor

Esra Koçoğlu

• Department of Microbiology, Abant Izzet Baysal University, School of Medicine, 14280, Bolu, Turkey

autor

Aysegul Bukulmez

• Department of Microbiology, Kirikkale University, School of Medicine, 71100, Kirikkale, Turkey

autor

Yasin Yoldas

• Zubeyde Hanim Maternity Hospital and Childcare Center, 03100, Afyonkarahisar, Turkey

autor

Pınar Aykurt

• Zubeyde Hanim Maternity Hospital and Childcare Center, 03100, Afyonkarahisar, Turkey

Bibliografia

• [1] Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass RI. Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis 2003; 9: 565–572 [PubMed][Crossref]
• [2] Dennehy PH. Rotavirus vaccines: an overview. Clin Microbiol Rev 2008; 21: 198–208 http://dx.doi.org/10.1128/CMR.00029-07[Crossref][WoS]
• [3] Estes MK, Kapikian AZ. Rotaviruses. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, et al, editors. Fields virology. 5th ed, Vol 2. Philadelphia: Lippincott Williams & Wilkins/Wolters Kluwer; 2006. p. 1917–1974
• [4] Gentsch JR, Laird AR, Bielfelt B, et al. Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs. J Infect Dis 2005; 192Suppl 1: S146–159 http://dx.doi.org/10.1086/431499[Crossref]
• [5] Santos N, Hoshino Y. Global distribution of rotavirus serotypes/genotypes and its implication for the development and implementation of an effective rotavirus vaccine. Rev Med Virol 2005; 15: 29–56 http://dx.doi.org/10.1002/rmv.448[Crossref]
• [6] Vesikari T, Matson DO, Dennehy P, et al. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med 2006; 354: 23–33 http://dx.doi.org/10.1056/NEJMoa052664[Crossref]
• [7] Ruiz-Palacios GM, Pérez-Schael I, Velázquez FR, et al. Safety and efficacy of an attenuated vaccine against severe rotavirus gastroenteritis. N Engl J Med 2006; 354: 11–22 http://dx.doi.org/10.1056/NEJMoa052434[Crossref]
• [8] Linhares AC, Velázquez FR, Pérez-Schael I, et al. Efficacy and safety of an oral live attenuated human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in Latin American infants: a randomised, double-blind, placebo-controlled phase III study. Lancet 2008; 371: 1181–1189 http://dx.doi.org/10.1016/S0140-6736(08)60524-3[Crossref]
• [9] Jakab F, Meleg E, Bányai K, et al. One-year survey of astrovirus infection in children with gastroenteritis in a large hospital in Hungary: occurrence and genetic analysis of astroviruses. J Med Virol 2004; 74: 71–77 http://dx.doi.org/10.1002/jmv.20148[Crossref]
• [10] Das BK, Gentsch JR, Cicirello HG, et al. Characterization of rotavirus strains from newborns in New Delhi, India. J Clin Microbiol 1994; 32: 1820–1822 [PubMed]
• [11] Gentsch JR, Glass RI, Woods P, et al. Identification of group A rotavirus gene 4 types by polymerase chain reaction. J Clin Microbiol 1992; 30: 1365–1373
• [12] Bányai K, Gentsch JR, Schipp R, et al. Dominating prevalence of P[8],G1 and P[8],G9 rotavirus strains among children admitted to hospital between 2000 and 2003 in Budapest, Hungary. J Med Virol 2005; 76: 414–423 http://dx.doi.org/10.1002/jmv.20372[Crossref]
• [13] Gouvea V, Glass RI, Woods P, et al. Polymerase chain reaction amplification and typing of rotavirus nucleic acid from stool specimens. J Clin Microbiol 1990; 28: 276–282 [PubMed]
• [14] Kang G, Iturriza-Gomara M, Wheeler JG, et al. Quantitation of group A rotavirus by real-time reverse-transcription-polymerase chain reaction: correlation with clinical severity in children in South India. J Med Virol 2004; 73: 118–122 http://dx.doi.org/10.1002/jmv.20053[Crossref]
• [15] Ceyhan M, Kanra G, Yeniay I, Ciliv G, Vesikari T. Rotaviruses in infants with diarrhea studied by viral RNA electrophoresis in Ankara, Turkey. Turk J Pediatr 1987; 29: 145–149 [PubMed]
• [16] Kurugöl Z, Geylani S, Karaca Y, et al. Rotavirus gastroenteritis among children under five years of age in Izmir, Turkey. Turk J Pediatr 2003; 45: 290–294 [PubMed]
• [17] Altindis M, Yavru S, Simsek A, Ozkul A, Ceri A, Koc H. Rotavirus infection in children with acute diarrhea as detected by latex agglutination, ELISA and polyacrylamide gel electrophoresis. Indian Pediatr 2004; 41: 590–594 [PubMed]
• [18] Çataloluk O, Iturriza M, Gray J. Molecular characterization of rotaviruses circulating in the population in Turkey. Epidemiol Infect 2005; 133: 673–678 http://dx.doi.org/10.1017/S0950268805003882[Crossref]
• [19] Karadag A, Acikgoz ZC, Avci Z, et al. Childhood diarrhoea in Ankara, Turkey: epidemiological and clinical features of rotavirus-positive versus rotavirus-negative cases. Scand J Infect Dis 2005; 37: 269–275 http://dx.doi.org/10.1080/00365540410020983[Crossref]
• [20] Bozdayi G, Dogan B, Dalgic B, et al. Diversity of human rotavirus G9 among children in Turkey. J Med Virol 2008; 80: 733–740 http://dx.doi.org/10.1002/jmv.21120[Crossref]
• [21] Altindis M, Bestepe G, Ceri A, Yavru S, Kalayci R. Frequency of rotavirus and enteric adenovirus infection in children with acute gastroenteritis. Med J SDU 2008; 15: 60–63
• [22] Staat MA, Azimi PH, Berke T, et al. Clinical presentations of rotavirus infection among hospitalized children. Pediatr Infect Dis J 2002; 21: 221–227 http://dx.doi.org/10.1097/00006454-200203000-00012[Crossref]
• [23] Maltezou HC, Zafiropoulou A, Mavrikou M, et al. Acute diarrhoea in children treated in an outpatient setting in Athens, Greece. J Infect 2001; 43: 122–127 http://dx.doi.org/10.1053/jinf.2001.0844[Crossref]
• [24] Cardoso DD, Soares CM, Dias e Souza MB, de Azevedo Mda S, Martins RM, Queiróz DA. Epidemiological features of rotavirus infection in Goiânia, Goiás, Brazil, from 1986 to 2000. Mem Inst Oswaldo Cruz 2003; 98: 25–29 http://dx.doi.org/10.1590/S0074-02762003000100004[Crossref]
• [25] Denno DM, Stapp JR, Boster DR, et al. Etiology of diarrhea in pediatric outpatient settings. Pediatr Infect Dis J 2005; 24: 142–148 http://dx.doi.org/10.1097/01.inf.0000151031.47761.6d[Crossref]
• [26] O’Ryan M, Díaz J, Mamani N, Navarrete M, Vallebuono C. Impact of rotavirus infections on outpatient clinic visits in Chile. Pediatr Infect Dis J 2007; 26: 41–45 http://dx.doi.org/10.1097/01.inf.0000247104.01291.71[WoS][Crossref]
• [27] Yokoo M, Arisawa K, Nakagomi O. Estimation of annual incidence, age-specific incidence rate, and cumulative risk of rotavirus gastroenteritis among children in Japan. Jpn J Infect Dis 2004; 57: 166–171 [PubMed]
• [28] Bányai K, Sas Y, Varga L, Szucs G. Survey of rotavirus infection in a Hungarian paediatric hospital. Acta Microbiol Immunol Hung 2004; 51: 431–435 http://dx.doi.org/10.1556/AMicr.51.2004.4.3[Crossref]
• [29] Meeting of the Immunization Strategic Advisory Group of Experts, April 2009-conclusions and recommendations. Wkly Epidemiol Rec 2009; 84: 220–236

Identyfikatory

DOI

10.2478/s11536-009-0130-6