Pseudarthrosis in fibrous dysplasia treated with bone morphogenetic protein

• Autorzy: Johannes Beckmann , Franz Kock , Markus Tingart , Juergen Goetz , Joachim Grifka , Jens Schaumburger
• Języki publikacji: EN

Abstrakty

EN

We present a case of pseudarthrosis in a patient suffering from polyostotic fibrous dysplasia of the right part of the body that was successfully treated with bone morphogenetic protein. Pseudarthrosis occurred after proximal femoral shaft fracture due to a motorcycle accident initially treated by intramedullary nailing. After revision, the patient was treated by pseudarthrosis debridement and grafting of bone morphogenetic protein-7/osteogenic protein-1, resulting in callus formation that allowed indolent full weight-bearing after 6 weeks. The underlying disease as well as the described treatment is discussed.

Słowa kluczowe

EN

Fibrous dysplasia; Pseudarthrosis; Bone morphogenetic protein; Osteogenic protein-1

• Czasopismo: Open Medicine
• Rocznik: 2008
• Tom: 3
• Numer: 3
• Strony: 377-379

Daty

wydano

2008-09-01

online

2008-07-10

Twórcy

autor

Johannes Beckmann

• Department of Orthopedic Surgery, University of Regensburg, 93077, Bad Abbach, Germany,

autor

Franz Kock

• Department of Orthopedic Surgery, University of Regensburg, 93077, Bad Abbach, Germany

autor

Markus Tingart

• Department of Orthopedic Surgery, University of Regensburg, 93077, Bad Abbach, Germany

autor

Juergen Goetz

• Department of Orthopedic Surgery, University of Regensburg, 93077, Bad Abbach, Germany

autor

Joachim Grifka

• Department of Orthopedic Surgery, University of Regensburg, 93077, Bad Abbach, Germany

autor

Jens Schaumburger

• Department of Orthopedic Surgery, University of Regensburg, 93077, Bad Abbach, Germany

Bibliografia

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• [6] Friedlaender G.E., Perry C.R., Cole J.D., Cook S.D., Cierny G., Muschler G.F., et al., Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions, J. Bone Joint Surg. Am., 2001, 83-A, Suppl 1,(Pt 2), S151–S158
• [7] Mont M.A., Ragland P.S., Biggins B., Friedlaender G., Patel T., Cook S., et al., Use of bone morphogenetic proteins for musculoskeletal applications. An overview, J. Bone Joint Surg. Am., 2004, 86-A, Suppl 2, 41–55

Identyfikatory

DOI

10.2478/s11536-008-0028-8