Review on analgesic effect of co-administrated ibuprofen and caffeine

• Autorzy: Andrzej Polski , Regina Kasperek , Karolina Sobotka-Polska , Ewa Poleszak
• Języki publikacji: EN

Abstrakty

EN

Pain is a symptom of many diseases and significantly affects the quality of life, so researchers are constantly seeking new substances to be used as analgesics. Other, easier way is to combine already known drugs which cause synergistic effects greater than additive, so that probability of drug-specific side effects can be reduced. Researchers showed that caffeine can be an effective analgesic adjuvant enhancing antinociceptive effect of ibuprofen in animals and humans. By using modern drug technology methods tablets containing well-soluble ibuprofen salt and caffeine can be easily prepared. Thanks to that combination, the therapeutic dose of ibuprofen can be lowered and the side effects may be reduced.

Słowa kluczowe

EN

analgesic; caffeine; ibuprofen; tablets

• Czasopismo: Current Issues in Pharmacy and Medical Sciences
• Rocznik: 2014
• Tom: 27
• Numer: 1
• Strony: 10-13

Daty

wydano

2014-06-01

otrzymano

2013-12-06

zaakceptowano

2014-02-14

online

2014-05-30

Twórcy

autor

Andrzej Polski

• Department of Applied Pharmacy, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland,

autor

Regina Kasperek

• Department of Applied Pharmacy, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland

autor

Karolina Sobotka-Polska

• Department of Organic Chemistry, Medical University of Lublin, Poland

autor

Ewa Poleszak

• Department of Applied Pharmacy, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland

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Identyfikatory

DOI

10.2478/cipms-2014-0003