Is cognitive processing affected in adults with hypospadias?: P300 study

• Autorzy: Hakan Tekeli , Hasan Koçoğlu , Cabir Alan , Mustafa Emir Tavşanlı , Halit Yaşar , Ercan Malkoç , Mustafa Tansel Kendirli , Ceyda Hayretdağ Örs , Ahmet Reşit Ersay , Handan Işın Özışık Karaman
• Języki publikacji: EN

Abstrakty

EN

Background: Hypospadias is a common urogenital system disorder. The frenulum, which is the most sensitive area of the glans penis, is not present in patients with hypospadias. This may lead to a failure in sexual and ejaculatory function, and cause emotional problems affecting cognitive processes. Aim: We aimed to study auditory Event Related Potentials (ERP) in patients with hypospadias to understand the status of cognitive function. Materials and Methods: Seventeen patients with hypospadias who presented to the Urology Outpatient Clinic of Çanakkale Military Hospital, and 11 healthy individuals of similar age were chosen. The auditory oddball paradigm with ERP from the Cz and Fz head regions were studied. The latency and amplitude of the P300 wave were measured. Results: Both, the study and control groups consisted of young males. Although the study group had a longer P300 latency and lower P300 amplitude when compared to control group, the results were not statistically significant (p: 0.059 and 0.346 respectively). Conclusion: Although the results are not statistically significant, our findings indicate that there may be cognitive changes in patients with hypospadias. Further studies of larger sample size and older patient cohorts are needed.

Słowa kluczowe

EN

Hypospadias; Event Related Potentials-P300; Cognition

• Czasopismo: Open Medicine
• Rocznik: 2014
• Tom: 10
• Numer: 1

Daty

otrzymano

2015-01-18

zaakceptowano

2015-09-14

online

2015-10-26

Twórcy

autor

Hakan Tekeli

• GATA Haydarpaşa Eğitim Hastanesi, Department of
  Neurology, Istanbul, Turkey

autor

Hasan Koçoğlu

• Gölcük Asker Hastanesi, Department of Urology,
  Kocaeli, Turkey

autor

Cabir Alan

• Çanakkale Onsekiz Mart Üniversitesi,
  Department of Urology, Çanakkale, Turkey

autor

Mustafa Emir Tavşanlı

• Okmeydani Education
  and Research Hospital Neurology Clinic Kaptanpasa Mahallesi
  Darülaceze Street No: 25 ZIP Code: 34384, Sisli, Istanbul, Turkey
• Okmeydanı Eğitim Araştırma Hastanesi,
  Department of Neurology, İstanbul, Turkey

autor

Halit Yaşar

• Ankara Mevki Asker Hastanesi, Department of Neurology,
  Ankara, Turkey

autor

Ercan Malkoç

• GATA Haydarpaşa Eğitim Hastanesi, Department of
  Urology, Istanbul, Turkey

autor

Mustafa Tansel Kendirli

• GATA Haydarpaşa Eğitim Hastanesi, Department of
  Neurology, Istanbul, Turkey

autor

Ceyda Hayretdağ Örs

• Çanakkale
  Onsekiz Mart Üniversitesi, Department of Neurology., Çanakkale,
  Turkey

autor

Ahmet Reşit Ersay

• Çanakkale Onsekiz Mart Üniversitesi,
  Department of Urology, Çanakkale, Turkey

autor

Handan Işın Özışık Karaman

• Çanakkale
  Onsekiz Mart Üniversitesi, Department of Neurology., Çanakkale,
  Turkey

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Identyfikatory

DOI

10.1515/med-2015-0059