Plasma-chemical modifications of cellulose for biomedical applications

• Autorzy: David Pavliňák , Veronika Švachová , Libor Vojtek , Jana Zarzycká , Pavel Hyršl , Milan Alberti , Lucy Vojtová
• Języki publikacji: EN

Abstrakty

EN

A 6-carboxycellulose (in medicine known as “oxidized cellulose” or “oxycellulose”) is one of the cellulose derivatives popular in the field of surgery. Health products based on oxidized cellulose are great local hemostatics with unique bactericidal and fully bioabsorbable effects. Traditional process of native cellulose oxidation is described as a complex radical reaction in strong acidic liquid medium doped by toxic nitrous radicals (NO*). Our plasma-chemical reaction demonstrates a new synthesis method of oxidized cellulose with unique bactericidal effect. This plasma-chemical treatment is based on atmospheric plasma discharge in liquid medium leading to the oxidation of polysaccharide molecules resulting in oxycellulose. Final oxycellulose properties were evaluated by infrared spectroscopy and carboxyl content determination. The biological impact showed a strong germicidal effect.

EN

Słowa kluczowe

EN

oxidized cellulose; oxycellulose; antibacterial; plasma-chemical treatment; plasma

• Czasopismo: Open Chemistry
• Rocznik: 2015
• Tom: 13
• Numer: 1

Daty

otrzymano

2014-01-31

zaakceptowano

2014-05-29

online

2014-11-17

Twórcy

autor

David Pavliňák

• Department of Physical Electronics, Masaryk University, 61137 Brno, Czech Republic,

autor

Veronika Švachová

• Faculty of Chemistry, Institute of Materials Chemistry, Brno University of Technology, 61200 Brno, Czech Republic

autor

Libor Vojtek

• Institute of Experimental Biology, Masaryk University, 61137 Brno, Czech Republic

autor

Jana Zarzycká

• Institute of Experimental Biology, Masaryk University, 61137 Brno, Czech Republic

autor

Pavel Hyršl

• Institute of Experimental Biology, Masaryk University, 61137 Brno, Czech Republic

autor

Milan Alberti

• Department of Physical Electronics, Masaryk University, 61137 Brno, Czech Republic

autor

Lucy Vojtová

• CEITEC – Central European Institute of Technology, Brno University of Technology, 61600 Brno, Czech Republic

Bibliografia

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Identyfikatory

DOI

10.1515/chem-2015-0030