Preparation and Characterization of Low Temperature Heat-Treated 45S5 Bioactive Glass-Ceramic Analogues

• Autorzy: Kailuo Xie , Lei Zhang , Xianyan Yang , Xiaoqing Wang , Guojing Yang , Licheng Zhang , Huifeng Shao , Yong He , Jianzhong Fu , Zhongru Gou
• Języki publikacji: EN

Abstrakty

EN

The 45S5 Bioglassr and its sintered bioactive glass-ceramic (BGC) have been widely investigated as bone implants, mainly for its ability to bond to hard tissues. However, high temperature treatment is not enough to improve its poor mechanical properties, but compromise its biologically relevant performances. The innovative BGC compositions based on the thermally treated 45S5 Bioglassr were developed by decreasing the P2O5 quantity and adding B2O3 (0-6%) into the Na2O–2CaO–3SiO2- based bioactive glasses (BG). The thermally treated BGCs were fully characterized from the microstructural and mechanical points of view and compared to each other. Their bioactivity and bio-dissolutionwere established by means of in vitro soaking tests. The new B2O3-added 45S5 BG analogues, named NCS-xB, can be transformed to crystalline phase (Na2Ca2Si3O9)-based BGCs of high compactness and bioactivity at a relatively low temperature heat treatment (≤ 900ºC), since their bioactivity is preserved. Our experimental results suggest that the new 45S5 BGC analogues with optimized composition exhibit improved micro- structural and mechanical properties, and are beneficial for making specific products such as porous scaffolds or composites for bone defect repair.

Słowa kluczowe

EN

Na2Ca2Si3O9; 45S5 glass-ceramic analogue; B2O3 additive; Mechanical properties; 45S5 Bioglass®

• Czasopismo: Biomedical glasses
• Rocznik: 2015
• Tom: 1
• Numer: 1

Daty

otrzymano

2014-12-28

zaakceptowano

2015-06-09

online

2015-09-07

Twórcy

autor

Kailuo Xie

• Rui’an People’s Hospital & the 3rd Affiliated Hospital to Wenzhou Medical University, Rui’an 325200, China

autor

Lei Zhang

• Rui’an People’s Hospital & the 3rd Affiliated Hospital to Wenzhou Medical University, Rui’an 325200, China

autor

Xianyan Yang

• Zhejiang-California International Nanosystems Institute Zhejiang University, Hangzhou 310029, China

autor

Xiaoqing Wang

• Rui’an People’s Hospital & the 3rd Affiliated Hospital to Wenzhou Medical University, Rui’an 325200, China

autor

Guojing Yang

• Rui’an People’s Hospital & the 3rd Affiliated Hospital to Wenzhou Medical University, Rui’an 325200, China

autor

Licheng Zhang

• Rui’an People’s Hospital & the 3rd Affiliated Hospital to Wenzhou Medical University, Rui’an 325200, China

autor

Huifeng Shao

• Institute of Advanced Manufacturing
  Engineering, Department of Mechanical Engineering,
  Zhejiang University, Hangzhou 310027, China

autor

Yong He

• Institute of Advanced Manufacturing
  Engineering, Department of Mechanical Engineering,
  Zhejiang University, Hangzhou 310027, China

autor

Jianzhong Fu

• Institute of Advanced Manufacturing
  Engineering, Department of Mechanical Engineering,
  Zhejiang University, Hangzhou 310027, China

autor

Zhongru Gou

• Zhejiang-California International Nanosystems Institute Zhejiang University, Hangzhou 310029, China

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Identyfikatory

DOI

10.1515/bglass-2015-0008