In the article, the signiﬁcance and essence of management of intelligent manufacturing in the era of the fourth industrial revolution has been presented. The current revolution has a large impact on the operation of the company. Through the changes resulting from the application of modern technologies, production processes are also undergoing revolutions, which results in changes in such indicators of business development. Management of intelligent manufacturing is also a challenge for socially responsible activities; due to solutions of Industry 4.0, enterprises directly and indirectly inﬂuence environmental protection, which results in beneﬁts for all mankind. In the article, the analysis and assessment of management of intelligent manufacturing, using modern technologies during the production process, has been carried out, with particular emphasis on the components of management such as: monitoring, control, autonomy, optimization. Moreover, the impact of the above components of management on changes in the following indicators (KPI – Key Performance Indictors) has been evaluated, i.e. (1) quality, (2) rapidity of the production process implementation, (3) performance and (4) productivity, (5) decrease in waste generated during the technological process and (6) amount of consumed electricity. For the purposes of conducting the research, a case study has been used, developed due to the information shared by the company manufacturing machinery and equipment for the polymer processing industry, in which intelligent solutions of Industry 4.0 are being applied. The presented article is a signiﬁcant contribution to the current development of knowledge in the ﬁeld of implementing Industry 4.0 solutions for polymer processing. The article is a combination of theoretical and practical knowledge in the ﬁeld of management and practical industrial applications. It refers to the most current research trends.