High-order cumulant tensors carry information about statistics of non-normally distributed multivariate data. In this work we present a new efficient algorithm for calculation of cumulants of arbitrary orders in a sliding window for data streams. We show that this algorithm offers substantial speedups of cumulant updates compared with the current solutions. The proposed algorithm can be used for processing on-line high-frequency multivariate data and can find applications, e.g., in on-line signal filtering and classification of data streams. To present an application of this algorithm, we propose an estimator of non-Gaussianity of a data stream based on the norms of high order cumulant tensors. We show how to detect the transition from Gaussian distributed data to non-Gaussian ones in a data stream. In order to achieve high implementation efficiency of operations on super-symmetric tensors, such as cumulant tensors, we employ a block structure to store and calculate only one hyper-pyramid part of such tensors.