At present, the speed of production and its complexity increases with each passing year due to the shorter product life cycle and competition in the global market. This trend is also observed in the machine-building industry, therefore, in order to ensure the competitiveness of enterprises and reduce the cost of production, it is necessary to intensify production. This is especially true in the machining of complex parts that require a great number of setups, and technological equipment. The problem-oriented analysis of complex parts was carried out, the parts classification was structured and developed according to the design and technological features. This made it possible to offer advanced manufacturing processes for complex parts like levers, forks, and connecting rods. The flexible fixtures for specified complex parts were developed. The effectiveness of the proposed manufacturing processes, as compared with the typical ones, provides significant improvement in the production.