The Jawornik granitoids intrude, in vein-like form, a sequence of a polymetamorphic metavolcanic and metapelitic rocks of the Orlica-Śnieżnik Dome, Sudetes, Poland. This paper provides whole-rock geochemical data, sensitive high-resolution ion microprobe (SHRIMP) U-Pb zircon geochronological data as well as 40Ar-39Ar age determinations to constrain the genetic and temporal relationships of the different rock types forming these veins. Based on macroscopically visible features of the granitoids and their relationship with tectonic structures visible in the country rocks, four varieties of the Jawornik granitoids have been distinguished: amphibole- and biotite-bearing granites (HBG), biotite-bearing granites (BG), biotite- and muscovite-bearing granites (BMG) and muscovite-bearlng granites (MG). The Jawornik granitoids as a whole show a limited but significant variation in major element chemical composition, with SiO2 ranging from 65 to 76 wt.% (average 69.16 wt.%, n = 24). They are subalkalic, peraluminous and calc-alkaline [average A/CNK = 1.07, average (Na2O + K2O) = 7.75, average (Fe2O3t/(Fe2O3t + MgO) = 0.59]. Close inspection of their geochemical parameters showed that the samples investigated can be subdivided into two groups. The first group, the HBG, BG, and BMG varieties, comprising most of the granitoids in the Złoty Stok-Skrzynka Tectonic Zone, were formed by melting of greywackes or/and amphibolites. The MG, belonging to the second group, were formed by partial melting of a more felsic source. The HBG yielded a zircon U-Pb age of 351 ±1.3 Ma and well-defined Ar-399Ar plateau ages for hornblende (351.1 ±3.9 Ma) and coexisting biotite (349.6 ±3.8 Ma), indicating probably the oldest magmatic event in this region. Zircons from the MG, the youngest rock variety on the basis of their relationship with the tectonic structures in the host rocks yielded a U-Pb age of 336.3 ±2.4 Ma, though based on three points only. The biotites and muscovites from the BMG have Ar-39Ar plateau ages of 344.1 ±4.7 Ma and 344.6 ±3.8 Ma, respectively. These data, in combination with already published isotopic ages, suggest that the Jawornik granitoids intruded host rocks of the Orlica-Śnieżnik Dome in three stages, at ~350, ~344 and ~335 Ma.