Purpose: of this paper was demonstration a novel technique of laser cladding by experimentally composed Co-based metallic powder and forced cooling of the substrate by liquid nitrogen under cryogenic conditions, at the temperature -190°C, for producing clad layers with enhanced microstructure characteristic and properties. Design/methodology/approach: Technological tests of laser cladding were conducted by means of a high power fibre laser HPFL with maximum output power 3.0 kW, and six-axis robot. The experimental Co-based powder was composed for providing high abrasive wear resistance, high resistance for impact load, and also for corrosion resistance at elevated temperature. The unique and novel technique of forced cooling of the substrate was provided by immersing the specimens in the liquid nitrogen bath. The three coaxial nozzle head was designed and custom made to provide precise deposition of the powder delivered into the laser beam irradiation region. The scope of the study included tests of conventional laser cladding at free cooling in ambient air in a wide range of processing parameters, and also trials of laser cladding under cryogenic conditions. The test clad layers produced by conventional laser cladding and by the novel technique of laser powder deposition under cryogenic conditions were investigated and compared. Findings: The obtained results indicate that the novel technique of forced cooling the substrate by liquid nitrogen bath provides lower penetration depth, as well as low dilution of the clad, and also provides higher hardness of the clads. Additionally, it is possible shaping the geometry of the individual bead, providing high reinforcement and low width. Research limitations/implications: The presented results are based just on preliminary test of the novel technique of laser cladding under cryogenic conditions. Therefore, further study and detailed analyse of the influence of the cooling rate on the quality, microstructure, and properties of the deposited coatings are required. Practical implications: The study is focused on practical application of the novel technique for manufacturing of wear resistance coatings characterised with enhanced performance compared to conventional range of application of the laser cladding. Originality/value: Novel technique of laser cladding at forced cooling under cryogenic conditions was demonstrated. The powder used for cladding trials was experimentally composed (not commercially available). The experimental stand custom made was used with custom made powder feeding rate, and also with custom made coaxial nozzle head.