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EN
Any proof of a hypothesis or research thesis requires the researcher to use methods that are optimally selected according to the organizational capabilities of the researcher, the adopted research budget, and, above all, the adopted research assumptions. An important factor is to optimize the possibility of obtaining a research result that most closely reflects the surrounding cognitive reality. In economics, which is included in the field of social sciences, an important plane of analysis is the so-called data, which the researcher must process and, using statistical methods, carry out the process of falsification or confirmation of the research hypothesis. An activity that broadens the cognitive value is qualitative methods and, more specifically, the information obtained using them. In this way, the researcher creates a comprehensive research process, in which quantitative methods are compiled with qualitative methods. Such a study is referred to as a method of triangulation of methods, which allows the researcher to confront the representative result of quantitative and qualitative research.
PL
Każdy dowód hipotezy lub tezy badawczej wymaga od badacza zastosowania metod optymalnie dobranych do możliwości organizacyjnych badacza, przyjętego budżetu badawczego, a przede wszystkim przyjętych założeń badawczych. Ważnym czynnikiem jest optymalizacja możliwości uzyskania wyniku badań, który w największym stopniu odzwierciedla otaczającą rzeczywistość poznawczą. W ekonomii, zaliczanej do dziedziny nauk społecznych, ważną płaszczyzną analizy są tzw. dane, które badacz musi przetworzyć i przy użyciu metod statystycznych przeprowadzić proces falsyfikacji lub potwierdzenia hipotezy badawczej. Działaniem pogłębiającym wartość poznawczą są metody jakościowe, a dokładniej informacje uzyskane za ich pomocą. W ten sposób badacz tworzy kompleksowy proces badawczy, w którym metody ilościowe zestawione są z metodami jakościowymi. Takie badanie określa się mianem metody triangulacji metod, która pozwala badaczowi skonfrontować reprezentatywny wynik ilościowy z jakościowym rezultatem badań.
PL
Naukowcy nieustannie dążą do lepszego zrozumienia, przewidywania i ulepszania pożądanych właściwości materiałów. Jednym z narzędzi, które można w tym celu wykorzystać, jest sztuczna inteligencja.
PL
W niniejszej pracy przedstawiono stosowane obecnie metody oznaczania lotnych związków organicznych w wyrobach lakierowych: instrumentalną metodę chromatograficzną oraz wagową metodę różnicową. Oprócz charakterystyki poszczególnych technik uwagę poświęcono również na wskazanie wad i zalet każdej z nich. Podkreślono rolę komunikacji producentów z laboratoriami na etapie doboru metody analitycznej pod kątem badanego wyrobu.
EN
This paper presents the currently used methods for the determination of volatile organic compounds in varnish products: the instrumental chromatographic method and the differential gravimetric method. In addition to characterisation the different techniques, attention was also given to identifying the advantages and disadvantages of each. The role of communication between manufacturers and laboratories at the stage of selecting the analytical method for the tested product was emphasized.
PL
W artykule omówiono problematykę badań wybranych funkcji zabezpieczeniowych oraz automatyki za pomocą testera zabezpieczeń UTC GT2 produkcji Instytutu Energetyki w Warszawie. Zaprezentowano metody badań nietypowych funkcji zabezpieczeniowych wraz z omówieniem sposobów przygotowania testera do badań.
EN
The article discusses the issues of testing selected protection functions and automatics with the use of the UTC-GT2 protection relay tester produced by the Institute of Power Engineering in Warsaw. The methods of testing atypical protection functions are presented along with the methods of preparing the tester for testing.
EN
Magnetorheological (MR) fluids are classified as smart materials. They are non-homogeneous substances of complex composition and are characterised by complex rheological properties. In addition, the characteristics of their behaviour can be actively affected by the magnetic field, both in terms of its value and spatial orientation. This paper presents the results of shear stress measurements of a commercial magnetorheological fluid using a plate-plate type geometry with a modified working surface. The purpose of the study was to determine the effect of changing the roughness of the measuring plate on the obtained shear stress results. Controlled shear rate tests and Magneto Sweep measurements were carried out for three MR fluid layer heights. The tests were carried out at magnetic field induction in the range of 0 to 680 mT. The study showed that the measurement system's geometric parameters significantly affect the MR fluid's behaviour under test. It was shown that increasing the surface roughness can increase or decrease the measured value of shear stress depending on the test parameters.
PL
Ciecze magnetoreologiczne (MR) zaliczane są do grona materiałów inteligentnych. Są to substancje niejednorodne o złożonym składzie i charakteryzują się złożonymi właściwościami reologicznymi. Ponadto charakterystyki ich zachowania mogą być aktywnie kształtowane przez pole magnetyczne, zarówno ze względu na jego wartość, jak i orientację przestrzenną. W pracy przedstawiono wyniki pomiarów naprężenia stycznego komercyjnej cieczy MR z wykorzystaniem geometrii pomiarowej typu płytka–płytka o modyfikowanej powierzchni roboczej. Celem badań było określenie wpływu zmiany chropowatości płytki pomiarowej na uzyskiwane wyniki naprężeń ścinających. Przeprowadzono badania z kontrolowaną szybkością ścinania oraz pomiary typu Magneto Sweep dla trzech wysokości warstwy cieczy MR. Badania przeprowadzono przy indukcji pola magnetycznego w zakresie 0 do 680 mT. Badania wykazały, że parametry geometryczne układu pomiarowego istotnie wpływają na zachowanie się badanej cieczy MR. Wykazano, że w zależności od parametrów badania zwiększenie chropowatości powierzchni może powodować zwiększenie lub zmniejszenie rejestrowanej wartości naprężeń stycznych.
PL
Opracowanie nowej formulacji produktu leczniczego, wyrobu medycznego czy suplementu diety to niezwykle skomplikowany i złożony proces, który obejmuje szereg niezbędnych analiz potwierdzających jakość i przydatność tych produktów. Rozważania dotyczące bezpieczeństwa, a w przypadku produktów leczniczych również skuteczności działania (w rozumieniu mocy/aktywności) są nieodzownym elementem w trakcie opracowywania formulacji. Proces kontrolny powinien dotyczyć wszystkich etapów rozwoju produktu, począwszy od wytypowania substancji czynnej o charakterze leczniczym lub wspomagającej działanie lecznicze, aż po ostatni etap badań przedklinicznych przed testami na ludziach. Badania powinny być również kontynuowane po etapie komercjalizacji, dla produktów z rynku, w celu potwierdzenia odpowiedniej jakości, bezpieczeństwa, czystości i mocy produktu. Metody in vitro są kluczowymi testami stosowanymi przez środowisko naukowe oraz firmy branży farmaceutycznej do generowania wysokiej jakości informacji na temat bezpieczeństwa i skuteczności cząsteczek o potencjale terapeutycznym i nie tylko. Jaki jest cel badań in vitro? Jakich informacji dostarczają w procesie opracowywania nowych produktów? Jaki mają wpływ na branżę farmaceutyczną i w jaki sposób jej pomagają?
EN
The development of a new formulation of a drug, medical device or dietary supplement is an extremely complicated and complex process that includes a number of necessary analyses confirming the quality and potential of these products. Safety considerations, and in case of drugs also the potency (activity) considerations, are necessary steps in the formulation development. The control process should cover all stages of product development. From selecting on active ingredient with therapeutic purposes or supporting the therapeutic effect, up to the last stage of preclinical studies before clinical trials. Control activities should continue after the commercialization stage, for products from the market, in order to confirm the appropriate quality, purity and potency of the product in the production process. In vitro methods are key tests used by the scientific community and pharmaceutical companies to generate high-quality information on the safety and efficacy of drug candidates and more. What is the purpose of in vitro research? What information do they provide in the drug development process? What is their impact on the pharmaceutical industry and how are they helping it?
PL
W artykule dokonano wyboru metod badawczych właściwości użytkowych w zakresie zastosowania taśm uszczelniających z plastyfikowanego polichlorku winylu w przerwach roboczych i dylatacyjnych elementów konstrukcji żelbetowej. Szczególną uwagę zwrócono na wybór odpowiednich metod badawczych, w kontekście charakterystycznej budowy i zastosowania taśm w budownictwie mostowym, względem wymagań, jakie należy spełnić, aby wyrób budowlany był wprowadzony na rynek materiałów budowlanych.
EN
The article presents a selection of research methods for functional properties in the field of the use of waterstop made of plasticized polyvinyl chloride in working and expansion joints of reinforced concrete structure elements. Particular attention was highlighted to the selection of appropriate test methods, in the context of waterstop characteristic structure and application in bridge construction, in relation to the requirements that must be met for the construction product to be introduced to the market of building materials.
EN
Both the light- and heavy-duty sectors of the automotive industry are currently under unprecedented pressure from a wide range of factors, particularly in terms of environmental performance and fuel consumption. Test procedures have undergone massive changes and continue to evolve, meaning that standards are becoming much harder to meet, especially in Europe but also in other continents. Such developments force changes in testing methodology, the development of powertrains themselves and their aftertreatment systems and strategies and calibrations. This paper reports and summarises the topics of the PTNSS Congress and attempts a synthesis on the current status of the field of LD ad HD IC engines, hybrid powertrains and electric vehicles, engine fuel and oil and what the coming years may hold for the automotive and fuel industries and other allied fields.
EN
The key metrological issue of substance and energy balance in research engines is the precise determination of the elemental composition of the applied fuel and its net calorific value. This makes it possible to calculate the amount of heat brought with the fuel into the combustion chamber, as well as the amount and gas composition of the exhaust. However, to fully assess the energy quality of the fuel used, its ignition properties should also be estimated. They determine the combustion kinetics and, consequently, the course of gas pressure alterations and heat release in the cylinder, which have a direct impact on the indicated power and thermal efficiency of the engine. This article presents the methodology for carrying out this type of laboratory tests and their representative results concerning six different low-sulfur marine fuels used to feed marine engines at present. The considerations focus mainly on measurement technology, as well as the measuring apparatus applied today. Additionally some existing metrological difficulties that might be met were shortly described. The laboratory tests in question stand for the first stage of the program of testing a new kind of low-sulfur marine fuels in real operating conditions of a diesel engine, which was carried out at the Department of Ship Power Plants of the Gdańsk University of Technology.
EN
Purpose: The aim of this paper was to verify the necessity of devising a tool, method, procedure of selecting research methods and techniques for the research process, in order to increase the quality and reliability of the conducted research. Design/methodology/approach: Within the scope of the research process a questionnaire was used, which was distributed in two forms to management theoreticians and practitioners. 401 management science theoreticians and 118 management practice representatives were examined. Thus, the research problem was defined as follows: Is it necessary to develop (model, procedure, tool, approach) to the research process? Findings: Conclusions derived from the completed analysis of national and foreign literature on management sciences indicate the need to perform a diagnosis. The diagnosis refers to the development of a procedure for selecting methods and techniques for the sake of research processes in management sciences. The research carried out has identified the methods, procedures and approaches that are most relevant to the research process and its various components in management sciences. This makes it possible not only to determine the extent to which individual methods and techniques are used or combined, but also to identify certain regularities in the perception of the research process in this context and other variables that may influence the relevance of the appropriate choice of methods and techniques for the research process in management science in order to increase the reliability, level and quality of the research conducted. Research limitations/implications: The methodological and method-related correctness of the presented work is confirmed by the answers to the questions included in the questionnaires. They most often highlighted barriers in planning and conducting scientific research, obstacles beyond the methodological ones, mistakes most often made in scientific research in management sciences, the applicability of results to business practice. Practical implications: The conclusions of the research confirm that for the effective operation of the research process, it is necessary to develop a kind of 'behavioural algorithm' that will allow methods to be adapted to the posed research problem, once the gap has been defined, which will result in added value for practice. This is also confirmed by reactions of management practitioners to these statements. 89% of the surveyed practitioners believe that there is a need to develop a model, procedure, tool or approach to support the appropriate selection of methods for the research process. Social implications: In management sciences it is genuinely easy to create ‘new theories’ that are not finally verified. A swift introduction of new, recommended management-related concepts and methods, as well as their rapid rejection resulted in negative organisational changes. It would be difficult to determine the reasons why the applied methods lack effectiveness. Was the failure triggered by an inadequate method used for a management process or by its unskilful implementation. Originality/value: One verified the necessity of devising a tool, method, procedure of selecting research methods and techniques for the research process, in order to increase the quality and reliability of the conducted research. The elaborated methods, procedures or models were verified in practice with the aim of making the research reliable.
11
Content available Science and practice in research process
EN
Purpose: The aim of the article is to compare the results of research on the use of research methods and techniques in solving management problems and in verifying which of the two acceptable approaches in the research process dominates among practitioners and theoreticians of management sciences. Design/methodology/approach: The survey was conducted by means of a questionnaire. The research was addressed to management science theoreticians and management practitioners being the target group covering: 272 foreign universities; 21,024 foreign researchers; 93 domestic universities; 2,307 domestic researchers; 52 foreign companies, 183 domestic companies. As a result of the research effort, 401 representatives of management science theoreticians and 118 practitioners were examined. Findings: The carried-out research has made it possible to identify methods, procedures, techniques and approaches that are most relevant to research processes in management sciences. Furthermore, both scientists and practitioners of management sciences use the same research methods. Research limitations/implications: It should be stated that management science and the methods used in it should support business practice and, to some extent, provide guidance to managers and directors. Management should be treated as a normative science, the aim of which is to formulate the principles of effective and efficient functioning of enterprises. Practical implications: The conclusions resulting from the carried-out research explicitly indicate that both scientists and practitioners of management sciences use the same research methods, i.e.: analysis of documentation, questionnaire, observation and interview. Research results obtained during the research process in the field of management sciences should be applied in practice. Social implications: Owing to the involvement of scientists and practitioners in research, it can be concluded that, while defining a research problem, it is difficult to choose a single method which allows for a full and thorough diagnosis of the problem under investigation. It is therefore necessary, in the research process, to use a variety of methods which will provide a comprehensive response to the posed problem. Originality/value: The research carried out has made it possible to identify methods, procedures, techniques and approaches that are most relevant to the research processes in management sciences. They were carried out in two stages. The commitment of both theoreticians and practitioners to the research process resulted in a broader interpretation of management sciences and allowed the author to diagnose the studied issues more fully and thoroughly.
12
Content available Observation as a research method in social science
EN
Purpose: The aim of the article was to present the main ideas of observation viewed as one of the oldest research methods in social science. Design/methodology/approach: As a result of the undertaken research process, 401 theoreticians of management science were surveyed. Findings: Conclusions resulting from the conducted research clearly indicate that among the methods applied in practice for research in management science, based on observation of facts and classification used in the general methodology of inductive sciences, it is necessary to employ observations carried out in natural conditions and observations-interventions that take place as part of management activities in the surveyed entities. Originality/value: Management science and methods should support business practice and, to some extent, provide guidance to executives and managers.
EN
Purpose: The aim of the paper was to determine whether the purpose of the discipline, i.e. management science, is to support the practical aspects of economic life. Design/methodology/approach: In order to find answers to the said research questions, 401 theoreticians of management science were surveyed by means of an anonymous survey questionnaire. Findings: Conclusions resulting from the conducted research and the analysis of the literature clearly indicate the need to carry out research work embedded in both theoretical and practical terms. Originality/value: It is indicated that the main disadvantage associated with the management science is the impermanence of the claims made. It should be remembered that it also cover theoretical research within its scope, as no science can develop without theoretical background. It is also worth noting that the relationship between the management science and business practice is bilateral and additionally complex.
EN
Purpose: Developing a procedure for the course of the research process for management science and practice. An original procedure for the course of the research process in management and quality sciences was presented. Design/methodology/approach: Based on the analysis of domestic and foreign literature, as well as the model of the research process, five stages have been defined, which should be included in the procedure of the research process. They included: selection of the research subject, determination of the nature of the research, determination of the transparency of the research purpose, selection of the method of conducting the research, determination of the size of the studied sample. Findings: Taking into account the model of the research process, a procedure for conducting research was developed. Research limitations/implications: The developed procedure is a premise for conducting further research in the direction of assigning research methods and techniques to individual elements of the research process stages in management and quality sciences. Selection of appropriate methods and research techniques will translate into the verification of research hypotheses, such as and answers to research questions. Practical implications: First of all, it is important to develop a procedure for the course of the research process for management science and practice, and then, for individual stages of this process, assign appropriate research methods and techniques. Social implications: The author's procedure for the course of the research process presented in this article is a response to how to operationalize phenomena in the sciences on management and quality and thus translate into research related to Industry 4.0. Originality/value: The developed procedure for the course of the research process allows for detailed familiarization and carrying out of scientific research, and in particular for a precise presentation of the characteristics of the tested entity, dispelling doubts regarding the transparency of the conducted research, appropriate description of the method of conducting the research, and determining the size of the research sample.
EN
In an ever changing business environment it is necessary for management accounting scholars, researchers and practitioners to be able to comprehend and facilitate change. The ability to constantly change research approaches to be appropriate to the research project is important for success. Research indicates that grounded theory and case study are two approaches that can be used in management accounting research. However, rarely used in management accounting research, it has the potential to contribute at all levels of management accounting research. The paper provides an individual account of using this approach. The purpose of this study was to provide guidelines for using a hybrid of grounded theory and case study methodologies in management accounting research.
PL
W ciągle zmieniającym się środowisku biznesowym konieczne jest, aby naukowcy z dziedziny rachunkowości zarządczej, badacze i praktycy byli w stanie zrozumieć i ułatwić zmianę. Zdolność do ciągłej zmiany podejść badawczych w celu dostosowania ich do projektu badawczego jest bardzo ważna dla sukcesu. Badania wskazują, że ugruntowana teoria i studium przypadku to dwa podejścia, które można zastosować w badaniach rachunkowości zarządczej. Jednak rzadko stosowane w rachunkowości zarządczej badanie ma potencjał, aby przyczynić się do badań na wszystkich poziomach rachunkowości zarządczej. Artykuł przedstawia indywidualne podejście do stosowania tego podejścia. Celem tego badania było przedstawienie wytycznych dotyczących stosowania mieszanki ugruntowanej teorii i metodologii studium przypadku w badaniach rachunkowości zarządczej.
16
Content available remote Assessing tram infrastructure safety using the example of the city of Gdańsk
EN
Analysis of Gdańsk tram network statistics shows that incidents are quite frequent (about 650 within five years) and mostly involve collisions and crashes. As well as reducing the tram systems’ efficiency and reliability, incidents have a negative effect on road safety. As Polish cities extend their tram networks, they must also ensure that their existing networks are safe. This is to be achieved by conducting safety assessments. The article presents different assessment methods, at different stages of tram infrastructure lifecycle, providing a basis for a comprehensive diagnosis and recommendations for improvement. The objective of the study was to conduct a comprehensive safety assessment and analysis of the existing and planned tram network across Gdańsk, using different study methods and tools.
PL
Analiza danych statystycznych dotyczących zdarzeń na sieci tramwajowej Gdańska wskazuje na dużą liczbę ich występowania (ok. 650 w ciągu 5 lat). Największy udział tych zdarzeń dotyczy kolizji i wypadków, wpływających nie tylko na sprawność i niezawodność funkcjonowania systemu tramwajowego, ale przede wszystkim na bezpieczeństwo ruchu. Rozwój sieci tramwajowej w wielu miastach w Polsce oraz konieczność zarządzania bezpieczeństwem na sieci istniejącej wymaga prowadzenia oceny bezpieczeństwa. W artykule przedstawiono metody tej oceny, na etapach cyklu życia infrastruktury tramwajowej, co pozwoliło na kompleksową diagnozę oraz sformułowanie rekomendacji i zaleceń co do działań naprawczych. Celem prowadzonych badań była kompleksowa ocena i analiza bezpieczeństwa istniejących i planowanych linii tramwajowych na terenie Gdańska, z wykorzystaniem różnych metod i narzędzi badawczych.
17
Content available remote Innowacyjne metody diagnostyki rozjazdów kolejowych
PL
Niniejsza praca poświęcona jest procesowi diagnostyki rozjazdów kolejowych z wykorzystaniem innowacyjnych metod badawczych. Przedstawiono wyniki badań i analiz przeprowadzonych na rozjazdach z wykorzystaniem skanera do trójwymiarowych pomiarów profili szyn kolejowych w celu wczesnej diagnostyki uszkodzeń iglic, opornic i krzyżownic. W pracy przedstawiano metodę badań oddziaływań dynamicznych generowanych przez ruch kolejowych na rozjazdach z podkładkami pod podkładowymi w celu oceny wpływu podkładek na wibroizolacyjności i trwałości konstrukcji rozjazdu.
EN
This work is devoted to the process of diagnosis of railway turnouts with the use of innovative research methods. The results of tests and analyzes carried out on switches with the use of a scanner for three dimensional measurements of railway rails profiles were presented for early diagnosis of damage to spiers, resistors and crossings. The paper presents the method of testing dynamic interactions generated by railway traffic on switches with underlay pads in order to assess the impact of washers on the vibro-isolation and durability of the turnout structure.
EN
The research methodology of family businesses is increasingly becoming the subject of scientific discussion that shows how difficult and complex task it is. Research area is located on the border of several disciplines, which raises significant methodological problems. Qualitative methods are useful for studying the problems of small family businesses, in particular related to the sphere of issues of identity, culture, values and the relationship between the family and the company. Qualitative methods allow for more efficient acquisition of reliable data on ‘sensitive’ subjects in comparison with quantitative methods. It is equally important to provide information about the complex social processes that are better studied with open methods. The methodology of qualitative research is not without its limitations. First of all, by definition it poses problems of generalization, and thus also theorizing. Research results are burdened with considerable subjectivity which can be transformed into inter-subjectivity by using different methods and perspectives. In the qualitative studies of small family businesses methodological pluralism which allows the creation of mixed research programs can be postulated. Combining quantitative and qualitative methods in one research program may provide important, but not always commensurate results. One can also point to the need for methodological triangulation and therefore the use of different, complementary research methods and techniques that will allow to describe the studied small family company in its entire complexity. The example of duo-ethnography provides the possibility to achieve a high level of relational demands allowing for the creation of unique philosophy of the meeting, a deep entry into the unique history of the studied entity and ownership family and the adoption of prospects for the narrator and an expert person participating in the study.
PL
Celem artykułu jest przeanalizowanie możliwości zastosowania duo-etnografi i w badaniach dążących do poznania charakterystyki i problemów firm rodzinnych. Autorzy opisują kluczowe problemy związane z badaniami nad tą grupą podmiotów. Analizę przeprowadzono w oparciu o refleksję nad metodami stosowanymi w poznawaniu małych organizacji rodzinnych, porównania metod jakościowych i ilościowych oraz odniesień do mniej znanych metod badawczych, takich jak auto-etnografia, analiza porównawcza i liczne studia przypadków. W artykule wskazano na konieczność stosowania pluralizmu metodologicznego i wykorzystania różnych dostępnych technik badawczych, dzięki czemu możliwe będzie opisanie całej złożoności małej firmy rodzinnej.
PL
W artykule przedstawiono najnowsze metody nieniszczące wykorzystywane w badaniach w budownictwie. Zamieszczono przegląd i opis wybranych metod. Pokazano przede wszystkim przydatne do tego celu najnowsze metody nieniszczące. Można zaobserwować, iż rozwój metod badawczych jest ukierunkowany na ocenę w elementach i konstrukcjach innych cech niż wytrzymałość. Następuje on w kierunku konstruowania aparatury badawczej pozwalającej uzyskiwać precyzyjne dane odnośnie do struktury badanego elementu zarówno w skali makro, jak i mikro, a czasem i nano. Daje to możliwość pełniejszej oceny jakości wykonania poszczególnych elementów w obiekcie budowlanym i jego konstrukcji.
EN
This paper presents the latest non-destructive methods used in research in construction. The classification of the methods are included. The most interesting of the methods are described. A focus is on the latest nondestructive. Today the development of test methods is oriented towards the evaluation of the characteristics of structures and structural components other than strength. The development of equipment enabling one to obtain an accurate image of the inside structure of the tested element in macro, micro and nano scale. An extensive survey of the literature on the subject, which researchers and experts in the diagnostics of civil structures may find useful, is included.
PL
Aktualnie stosowane terapie lecznicze w wielu przypadkach nie są skuteczne. Z tego względu poszukuje się nowych związków aktywnych, czynnych biologicznie, które mogłyby w przyszłości zostać wprowadzone na rynek jako leki. Związki te często pozyskuje się z roślin lub syntetyzuje de novo. Zanim jednak nowy związek zostanie wprowadzony jako środek leczniczy, jego aktywność musi zostać szczegółowo przebadana. Molekularny mechanizm działania jest niezwykle istotny dla planowania terapii oraz zapobiegania ewentualnym skutkom ubocznym, jakie mogą pojawić się w trakcie leczenia. Bardzo ważnym aspektem jest określenie, czy badany związek jest genotoksyczny. Pośredni lub bezpośredni wpływ związków na materiał genetyczny powinien zostać dobrze poznany.
EN
Currently used therapies in many cases are not effective. For this reason, new biologically active compounds that could be marketed in the future as drugs are being sought. These compounds are often extracted from plants or synthesized de novo. However, before a new compound is introduced as a therapeutic agent, its activity must be carefully investigated. The molecular mechanism of action is extremely important for therapy planning and preventing possible side effects that may occur during treatment. It is very important to determine whether the tested compound is genotoxic. The direct or indirect influence of compounds on the genetic material should be well understood.
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