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Nanotechnology in artificial organ development and its application in diagnosis methodology in baroreflex sensitivity of patients with hypertension

Yambe T., Yoshizawa S., Sugita N., Tanaka A., Imachi K.

Biocybernetics and Biomedical Engineering

2007

Vol. 27, no. 1-2

65-70

Space in the human body is so limited that nanotechnology and micromachining technology are the important for the development of the internal artificial organs. Based on the nanotechnology, various kinds of artificial organ development have been performed in Tohoku University including artificial myocardium, artificial heart, rotary blood pump, artificial esophagus, and artificial sphincter. Furthermore, automatic control algorithm for the artificial heart and assisted circulation was applied to the invention of the new diagnosis methodology for the baroreflex sensitivity of the patients with hypertension. Successful clinical application of this new invention was performed. The technical application to the large range is expectable in artificial internal-organs development.

Convergence Analysis for Principal Component Flows

Yoshizawa S., Helmke U., Starkov K.

International Journal of Applied Mathematics and Computer Science

2001

Vol. 11, no 1

223-236

A common framework for analyzing the global convergence of several flows for principal component analysis is developed. It is shown that flows proposed by Brockett, Oja, Xu and others are all gradient flows and the global convergence of these flows to single equilibrium points is established. The signature of the Hessian at each critical point is determined.