Fungi of the genus Beauveria perform wide range of enzymatic activity. These entomopathogenic fungi are well-known biocatalysts for obtaining hydroxylated products of biotransformation. In presented study, Beauveria brongniartii DSM 6651 was involved in 2-phenylethanol biodegradation. Immobilized fungal mycelium both in agar-agar and calcium alginate showed excellent degradative activity towards selected chemical compound. In a laboratory scale, depending on the immobilization method it was possible to conduct complete degradation of substrate in 24 h to 48 h (>99%). Then process was scaled up. In semi-preparative scale, fungal biomass immobilized in calcium alginate was used for carrying out reaction in simplified model of flow bioreactor and stirred-batch bioreactor. In this case, it was possible to obtain complete degradation of 2-phenylethanol after 48 hours of the process(>99%).
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