Wyniki wyszukiwania - BazTech

Ograniczanie wyników

2 Polish Journal of Chemistry

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Synthesis, structure and Tuberculostatic Activity of N'-(amino-pyridyl-methylene)-hydrazinecarbodithioic Acid Methyl Esters

Orlewska C.

Polish Journal of Chemistry

2001

Vol. 75, nr 9

1237-1245

The methods of preparation of the title esters from imidates or amidrazones are described, and structures of the compounds are elucidated on the basis of 1H, 13C-NMR, 2D-NMR spectra and X-ray diffraction method. Tuberculotic activity was also studied.

Crystal and molecular structures of 1,1-bis(methylthio)-4-(2-pyridyl)-2,3,5-triaza-1,3-pentadiene and its 5-phenyl derivative

Główka M., Martynowski D., Olczak A., Kozłowska K., Ołubek Z., Orlewska C., Foks H.

Polish Journal of Chemistry

1999

vol. 73 nr 5

845-851

Structures of the two dimethylthiomethylene-2-pyridinecarboxamide hydrazones have been examined spectroscopially and by X-ray diffraction to establish the dominant tautometric form and conformation. The two crystal structures are very similar with approximately planar conformation and intramolecular hydrogen bond between 4-imine group as hydrogen donor and pyridyl N atom as an acceptor. Several significant differences found may be easily explained by phenyl substitution in one of the compounds. The benzene ring in compound 2 is twisted by about 40o in relation to the mean molecular plane due to packing forces. An interesting feature of the structures is the deviation of the pyridyl ring by 11-14o from the mean 2,3,5-triaza-1,3-pentadiene plane in the two structures, despite the intramolecular hydrogen bond spanning the two fragments. It agrees with the elongation of C(4)-pyridine bond to 1.488 A, which corresponds with the lack of conjugation between p electrons of the pyridine ring and a lone pair at adjacent N(4) atom.