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1
Content available Design and manufacture of customized medical implants
Elgalal M., Komorowski P., Makowski K., Styczyński A., Ulański P., Kubiak T., Sawicki J., Domżalski M., Walkowiak B.
Engineering of Biomaterials
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2018
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Vol. 21, no. 148
36
2
Content available Comprehensive biological evaluation of biomaterials used in spinal surgery
Komorowski P., Kamińska M., Jakubowski W., Szymański W., Walczyńska M., Siatkowska M., Działoszyńska K., Sokołowska P., Białkowska K., Wasiak T., Elgalal M., Makowski K., Kierzkowska A., Ciupik L., Walkowiak B.
Engineering of Biomaterials
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2017
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Vol. 20, no. 143 spec. iss.
23
3
Content available Control of the biological response to metallic biomaterials through application of the DLC coatings with dopants
Bociąga D., Olejnik A., Jastrzębski K., Jędrzejczak A., Świątek L., Grabarczyk J., Sobczyk-Guzenda A., Kamińska M., Jakubowski W., Komorowski P., Niedzielski P.
Engineering of Biomaterials
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2016
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Vol. 19, no. 138 spec. iss.
94
4
Content available remote Acoustic maps of the sound level distribution inside the laboratory of the department of rail vehicles
Komorowski P., Szymański G. M.
Journal of Mechanical and Transport Engineering
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2015
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Vol. 67, No. 3
13--21
EN
The article presents the acoustic models of noise distribution which is caused by the working devices being a part of the laboratory equipment in the Department of Rail Vehicles at the Faculty of Machines and Transportation in Poznan University of Technology. The research was based on the measurements of the sound pressure levels corrected with the frequency characteristics A. The measurements were carried out when the technical objects, located in the educational posts inside the laboratory, had been in operation conditions. Based on the measurements and the assumptions of the method for stationary spatial transformation of sound field, the acoustic maps of the root-mean-square sound level values distribution were elaborated. The aim of this research was to analyze and to evaluate the noise level distribution affecting on the people during the lectures in the laboratory of rail vehicles.
PL
W artykule przedstawiono analizę propagacji hałasu podczas pracy urządzeń będących częścią wyposażenia laboratorium budowy pojazdów Zakładu Pojazdów Szynowych Politechniki Poznańskiej. Przeprowadzono badania polegające na pomiarach poziomu ciśnienia akustycznego skorygowanego za pomocą charakterystyki częstotliwości A. Pomiary wykonywano podczas pracy obiektów technicznych znajdujących się na stanowiskach dydaktycznych wewnątrz pomieszczenia. Na podstawie badań i założeń metody stacjonarnej transformacji przestrzennej pola dźwiękowego opracowano mapy akustyczne rozkładu poziomów wartości skutecznych dźwięku. Celem badania była analiza i ocena rozkładu hałasu podczas prowadzenia zajęć dydaktycznych wewnątrz laboratorium.
5
Content available The significance of the safety network in the financial system of an open economy
Komorowski P.
Ekonomia i Zarządzanie
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2015
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Vol. 7, no. 4
23--29
EN
In the article solving of a research problem presented in the introduction of the article is described. The aim of the article is to explore and verity the hypothesis that the complete structure of the Safety Network is the tool towards greater stability of the financial system. The research was based on a methodology that included descriptive and comparative analysis. The bibliography of the article consist of scientific works, as well as reports and expertise knowledge. The results of the research present the new structure of the safety network institutions that can be applied to the business practice and the theory of the financial markets. This arrangement broadens the structure and functions of the Safety Network and should result in better stability of the financial system, especially in relation to crisis.
6
Content available Ocena potencjalnych strat popowodziowych w wybranych dzielnicach Warszawy
Feluch W., Komorowski P.
Zeszyty Naukowe SGSP / Szkoła Główna Służby Pożarniczej
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2013
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Nr 45 (1)
27--48
PL
W artykule oceniono zagrożenie powodziowe i wielkość potencjalnych strat powodziowych w dwóch dzielnicach Warszawy – Wilanów i Praga Południe.
EN
The paper presents the issue of flood losses in selected districts of Warsaw. Process analyses of historical floods in the city. On the basis of historical data identified the areas most commonly inundated during the flood, a typification method for estimating potential losses of floods in two districts of the city. The conclusions of the work relates to the size of potential losses, the negative trend of their and infrastructure of flood protection.
7
Content available DLC coating doped by specified elements as a biomaterial designed for individual patient needs
Bociąga D., Szymański W., Jakubowski W., Komorowski P., Niedzielski P.
Engineering of Biomaterials
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2013
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Vol. 16, no. 122-123 spec. iss.
8--9
EN
Currently, there are more and more new materials (nanomaterials) proposed for biological and medical applications. They are, among other things, the effect of surface modification. One of the most frequently used techniques, fairly widespread, is plasmo-chemical method of diamond-like carbon (DLC) coating fabrication. There is many alterations of them, nevertheless all are characterized by short duration of the process and its economics. The final result does not require additional finishing treatments and the required coating properties can be controlled and obtained by selecting appropriate process parameters. Good mechanical and tribological properties, high corrosion resistance and its tolerance by biological systems have been documented in the literature. However, given the very wide range of applications of biomaterials found over time that the properties of carbon coatings are not always sufficient. The research conducting by scientific centres around the world have shown, however, that surface properties can be controlled by introducing specified elements into the DLC layer. Each of these added elements causes some properties change. Taking into consideration that we are dealing with biomaterials – the materials which are used in very harsh and demanding environment of a living organism, which also have a strong intra-individual variability, the solution in the form of material designed adequately to the needs of the individual patient is even more attractive and desirable. The DLC coatings doped by silver fulfilling constitute an innovative materials for biomedical application and are the subject of our investigations.
8
Content available Biologiczna ocena warstw węglowych domieszkowanych srebrem
Jakubowski W., Komorowski P., Bociaga D., Batory D., Niedzielski P., Walkowiak B.
Engineering of Biomaterials
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2012
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Vol. 15, no. 116-117 spec. iss.
89
PL
Postęp w naukach biologicznych i medycznych jest obecnie coraz silniej uzależniony od gromadzenia i poddawania analizie informacji o wzajemnych relacjach między komórkami żywych organizmów a powierzchniami materiałów abiotycznych. Szczególnie istotne jest to w dziedzinach związanych z wykorzystaniem biomateriałów, ale taka zależność jest też silnie widoczna w obszarze obejmującym przemysł przetwórczo-spożywczy. Oddziaływania materiał - komórka żywa, w znacznej mierze wykraczają poza dotychczas postrzegany zakres standardowego wykorzystania biomateriałów, a odkrycia na polu interakcji powierzchni materiałów z komórkami mają coraz większe znaczenie w prawidłowym użytkowaniu nowoczesnych systemów dystrybucji wody pitnej, a także przemysłowych systemów chłodzenia i obiegu cieczy. Wspomniany postęp stawia kolejne wyzwania przed inżynierią materiałową, która odpowiada za opracowywanie nowych technologii i materiałów mających spełniać coraz bardziej rygorystyczne oczekiwania użytkowników. Lepsze zrozumienie zależności w jakich pozostaje układ środowisko - organizmy żywe - materiał inżynierski prowadzą do wyeliminowania materiałów stwarzających potencjalnie zagrożenie, z jednoczesnym wprowadzeniem nowych materiałów, lepiej spełniających swoje funkcje. W procesie opracowania materiałów o wysokiej biozgodności uwagę naukowców w dużej mierze skupia grupa problemów związanych z zasiedlaniem powierzchni abiotycznych przez mikroorganizmy. Ograniczenie lub wyeliminowanie procesu kolonizacja powierzchni biomateriałów, zwykle prowadzącego do rozwinięcia się trudno zwalczanego biofilmu, stanowi istotne wyzwanie dla nowoopracowywanych biomateriałów. W literaturze fachowej dostrzegane są niekorzystne efekty, obserwowane przede wszystkim w praktyce klinicznej, do jakich doprowadza rozwiniecie się biofilmu na powierzchniach implantów. Opisywany jest także efekt wzrostu oporności takich kolonii bakteryjnych na działania układu immunologicznego oraz farmakoterapię. Jedną z możliwych modyfikacji powierzchni, pozwalających na ograniczenie zasiedlania ich przez mikroorganizmy, jest wprowadzenie elementów o działaniu bakterio- i grzybobójczym. W Instytucie Inżynierii Materiałowej opracowany został materiał, wytwarzany metodą hybrydową RF PACVD/MS, łączący bioinertny charakter warstw węglowych z bakteriobójczymi właściwościami jonów srebra. Powłoka tego typu pozwala na znaczące ograniczenie adhezji bakterii prowadzącej do rozwoju biofilmu na powierzchni materiału, przy jednoczesnej znikomej cytotoksyczności dla komórek organizmów wyższych. Wyniki eksperymentów prowadzonych z wykorzystaniem modelowych hodowli bakterii E.coli (DH5a) oraz komórek ludzkich osteoblastów (Saos 2) i komórek śródbłonka (EA.hy 926) w pełni potwierdziły zakładane właściwości nowego materiału.
EN
Progress in biological sciences and medicine is today increasingly dependent on collecting and examining information on the relationship between the cells of living organisms and abiotic surfaces of different materials. This is especially important in areas related to the use of biomaterials, and this dependence is particularly evident in certain areas such as the food industry. Interactions between material - living cells, has until recently been largely considered outside the scope of the standard use of biomaterials. The discovery of cell interactions with material surfaces are of growing importance in the proper use of modern drinking water distribution systems, industrial cooling systems and fluid circulation. This progress poses new challenges for materials engineering, which is responsible for the development of new technologies and materials that must meet increasingly stringent standards. With a better understanding of relationships present in such a system: environment - living cells - material engineering, it will be possible to eliminate any materials that poses a potential threat, and introduce new materials, that perform their functions more efficiently. In the process of developing materials with high a degree of biocompatibility, much of the research has focused on the problem of abiotic surface colonization by different microorganisms. One of the most significant challenges in developing new biomaterials is the reduction or elimination of biomaterial surface colonization, which usually leads to the development of a biofilm. In the literature the adverse effects of such interactions have been observed, primarily in clinical practice and the development of biofilms on the surface of implants. Increased resistance of these bacterial colonies to the human immune system and drug therapy has also been described. One possible material surface modification, which could reduce microorganism colonization, is the introduction of elements that exhibit bactericidal and fungicidal activity. The Institute of Materials Engineering has developed a material produced using a hybrid method RF PACVD/MS, which combines the bioinert nature of carbon layers and the bactericidal properties of silver ions. Such a coating can significantly reduce the degree bacterial adhesion, which results in the development of a biofilm on the surface materials, whilst having a negligible cytotoxic effect on the cells of higher organisms. Results of experiments conducted using the model bacterium E. coli culture (DH5a) together with human osteoblastic (Saos 2) and endothelial cells (EA.hy 926) have fully confirmed the assumed properties of this new material.
9
Content available Analiza zmian w ekspresji genów cyklu komórkowego w komórkach osteoblastów hodowanych na powierzchniach stopów tytanu
Walkowiak-Przybyło M., Komorowski P., Jakubowski W., Klimek L., Walkowiak B.
Engineering of Biomaterials
|
2012
|
Vol. 15, no. 116-117 spec. iss.
46--48
10
Content available Proliferacja osteoblastów Saos-2 oraz komórek endotelialnych EA.hy 926 na polerowanych i piaskowanych powierzchniach stopów tytanu Ti6Al4V i Ti6Al7Nb
Walkowiak-Przybyło M., Walczyńska M., Komorowski P., Klimek L., Walkowiak B.
Engineering of Biomaterials
|
2011
|
Vol. 14, no. 109-111 spec. iss.
39--41
11
Content available Endothelial cell proteome changed by contact with surfaces of biomaterials
Komorowski P., Jerczyńska H., Pawłowska Z., Walkowiak M., Walkowiak B.
Engineering of Biomaterials
|
2009
|
Vol. 12, no. 89-91
30
EN
Biomaterials used for medical implants or instruments production can cause numerous undesirable effects in human organism. They may affect cells being in a direct contact with them and can cause changes in genes expression, and as a consequence, also in protein profile of these cells. The aim of the present work was to examine an effect of medical steel 316L, poly-paraxylylene (Parylene) and nanocrystalline diamond (NCD) surfaces on protein expression in human endothelial cell line EA.hy 926.Cells were grown in Dulbecco’s MEM (DMEM) supplemented with antibiotics (penicillin and streptomycin), glucose, 10% heat inactivated fetal bovine serum and HAT-supplement. After 48h of incubation cells were washed with PBS and treated with lysis buffer (7M urea, 2M thiourea, 4% CHAPS, 2 % IPG buffer pH 4-7, 1% DTT). Proteins were purified from cell lysates with 2-D CleanUp Kit, and concentration was assessed with 2D Quant Kit. After overnight rehydration of IEF strips (pH 4-7, 11cm), in the presence of purified proteins, isoelectric focusing procedure was performed until 40kVh. Then, stripes were equilibrated, and focused proteins were separated in 12,5% polyacrylamide gels (SDS PAGE). Silver stained gels were recorded with ImageScanner and analyzed with ImageMaster 2D Platinium 6.0 (GE Healthcare) software. Numerous changes in protein expression were detected in endothelial cells exposed to artificial surfaces of tested materials (see TABLE I).
12
Content available remote Interaction of parylene C with biological objects
Kamińska M., Okrój W., Szymański W., Jakubowski W., Komorowski P., Nosal A., Szymanowski H., Gazicki-Lipman M., Jerczyńska H., Pawłowska Z., Walkowiak B.
Acta of Bioengineering and Biomechanics
|
2009
|
Vol. 11, nr 3
19-25
EN
The aim of the present work was to examine the interactions of parylene C with such selected biological objects as: blood plasma proteins, platelets, endothelial cells, and bacterial biofilm produced by E. coli cells. The results obtained strongly support the thesis that parylene C is a material worth considering for biomedical use. Parylene C coating on polished medical steel significantly reduces platelet adhesion to this surface. On the other hand, in the case of the surface of machined medical steel coated with parylene C, the number of adhered platelets is significantly higher. This also means that surface texture of substrate material is very well reproduced by parylene C coating and is an important factor facilitating the platelet adhesion. Adsorption of plasma proteins at parylene C surface is very effective, and this finding confirms a notion that cell interaction with surfaces is mediated by the adsorbed proteins. In the light of the above, a high susceptibility of parylene C surface to bacterial colonization is easy to explain. The results showing reduced proliferation and changes in endothelial cell gene expression should also be seriously analysed when parylene C is considered for the use in contact with blood vessels.
13
Content available remote Zagadnienia historiografii na łamach "Kwartalnika Historii Nauki i Techniki" 1956-2005
Komorowski P.
Kwartalnik Historii Nauki i Techniki
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2006
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R. 51, nr 1
45-65
EN
The paper presents texts publisbed in "Kwartalnik Historii Nauki i Techniki" over tbe last fifty years tbat were devoted to bistoriograpby. The paper does not aspire to overview all such texts, and deals only witb selected publications tbat tbe autbor con- siders to be the most important in the field. A number of conclusions stem from the analysed material. First of all, considering all the texts published in the quarterly, it can be seen that there have been relatively few articles on historiography compared to the number of publictions in other fields, such as history of the exact or natural sciences, or broadly undersrtood humanities. There is no single explanation for that, but one factor might be that texts on historiography could be published in other joumals, which were specially dedicated to historiography. Another conclusion that stems from the analysis concems the content of the articles, which shows a lot of variation. Most articles deal with the historiography of the 18th century; there is also a substantial number of publications dealing with historiogra- phy in the 19th century.The subject- matter of the articles relates both to Polish and general (Greman, French) historiography. Among the quarterly's publications there have also been articles that present work in the field of history by such personages as M.D. Krajewski, M. Wiszniewski or F. Konieczny. A separate -and very interesting -group of articles is made up of scholarly autobiographies. Appearing in the section "Portraits", which carried autobiographies of Polish scientists from various disciplines, memoirs were published in the quarterly by eminent historians such as S. Kieniewicz, H. Wereszycki, K. Górski or M. Tyrowicz. These auto- biographies ere of greata importance for researchers of historiography. The authors of the memoirs not only gave interesting accounts of their private lives, but also presented their scholarly evolution and achievements, as well as sketched a picture of the milieu of historians.
14
Content available Płytki krwi w kontakcie ze stopem tytanu Ti6Al4V i z jego zmodyfikowanymi powierzchniami
Okrój W., Klimek L., Komorowski P., Walkowiak B.
Inżynieria Biomateriałów
|
2005
|
R. 8, nr 43-44
13-16
15
Content available Trombozgodność warstw NCD na powierzchni stopów tytanowych
Okrój W., Jakubowski W., Przybyszewska I., Pirek M., Komorowski P., Mruklik M., Szymański W., Kosęda P., Walkowiak B.
Inżynieria Biomateriałów
|
2004
|
R. 7, nr 35-36
29-32
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