Wyniki wyszukiwania - BazTech

Ograniczanie wyników

1 Wiadomości Chemiczne

1 2010

Znaleziono wyników: 1

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Perspektywy zastosowania nowych nanomateriałów węglowych w kontrolowanym uwalnianiu leków

Pacholczyk A.M., Terzyk A.P., Wiśniewski M.

Wiadomości Chemiczne

2010

[Z] 64, 1-2

23-44

Drug delivery systems have many advantages compared to typical therapy and due to progress in nanotechnology still new systems are proposed for this purpose. The major advantages are for example: applicability of drugs poorly soluble in water, controlled transport, combined therapy where one or more drugs can be simultaneously applied and generally, better efficiency. In this review we analyze a group of .model. drugs applied for testing of those systems [5] and pay also attention to other important drugs [7, 8, 13, 14]. The applicability of older (for example polymers [2]) as well as new nanomaterials (silicas [6, 7, 9, 10, 12.17], gels [6, 18]) in drug delivery systems is discussed. Special attention is paid to new carbon materials i.e. carbon nanotubes and carbon nanohorns (Figs. 1.3) [1, 2, 20.24, 28.41]. We report recent advances in this field showing the potential applicability of those materials in drug delivery systems. Special attention is paid to the systems where anti-cancer drug cisplatin was covalently bound to the edges or incorporated inside single-wall carbon nanohorns. We also discuss the applicability of buckysomes, especially in delivery of hydrophobic anti-cancer drugs. Finally reports about toxicity of new forms of carbon are discussed and it is shown that many of them lead to contradictory conclusions [22, 42.55].