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Application and properties of selected flavanones

Błazińska P., Sykuła A.

Biotechnology and Food Science

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2018

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Vol. 82, nr 1

61--74

EN

Flavanones, secondary plant metabolites, are one of the main group of flavanoids. They are widely spread in nature in many plants. The large diversity of structural structure of flavanones and controlled methods of modifying their molecules have a huge impact on biological activity. The present review will summarize the current knowledge about occurrence, obtaining by chemical synthesis, application and bioactivity of flavanones. Also, they are received from specific chemical synthesis. Flavanones have a great biological activity. Derivatives of flavanone have many different properties such as anti-inflammatory, anticancer, antioxidant, antimicrobial or hepatoprotective activities. These natural polyphenolic compounds are used in cosmetology, pharmacy and medicine. The demand and usage on them increases.

2

Determination of total contents of transition metals in selected granular black teas marketed in Poland

Sykuła A., Brodowska K., Więdłocha M.

Biotechnology and Food Science

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2014

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Vol. 78, nr 1

45--52

EN

The total contents of metals in three granulated black tea samples marketed in Poland were determined. Four elements consisting transition metals (Ni, Cu, Zn and Fe) were analyzed using flame atomic absorption spectrophotometry (FAAS). All examined tea brands contain considerable contents of the studied transition metals. Among the tested transition metals Fe (242-589 mg kg-1) was the most abundant one in the granular black tea imported from India. The highest value of Fe was analyzed in the cheapest tea, the smallest in the most expensive. The other metals are less abundant than Fe, their values varied from 8.50-8.90 for Ni, 7.80-10.4 for Cu and 8.13-12.6 for Zn mg kg-1. The accuracy of the proposed method was assessed by determining the recovery of metals from analyzed tea samples using the standard addition method. Recovery assays of nickel, copper, zinc and iron were demonstrated satisfactory, mean recoveries 99.29, 100.31, 99.94 and 99.79 %, respectively.

3

Polimorfizm - jego wpływ na substancje farmaceutyczne

Sykuła A., Łodyga-Chruścińska E., Zakrzewski M.

Zeszyty Naukowe. Chemia Spożywcza i Biotechnologia / Politechnika Łódzka

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2006

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Z. 70

93-106

PL

Polimorfizm jest obecnie ważnym zjawiskiem w dziedzinie farmacji. Istnieje wiele substancji farmaceutycznych wykazujących zjawisko polimorfizmu bądź pseudopolimorfizmu. Wiele farmaceutyków może posiadać różne struktury krystaliczne, co ma istotny wpływ na właściwości postaci leku. W tym celu wykonuje się różnorodne analizy odmian polimorficznych. W oparciu o dane literaturowe przedstawiono przekrojowy opis możliwych struktur krystalicznych, ich właściwości, zależności między strukturą a właściwościami oraz najważniejsze techniki badań odmian polimorficznych różnych leków (m.in. metody rentgenowskiej analizy dyfrakcyjnej, metody spektroskopowe, metody termiczne).

EN

Polymorphism phenomenon plays a very important role in the pharmacy. It is well-established that many pharmaceutical solids can exist in several polymorphic or pseudopolymorphic forms. Polymorphs of pharmaceutical substances have crucial influence on drug properties. Therefore, there are various analytical methods characterizing polymorphic crystal forms. Based on literature data authors review the key elements of polymorph characterization: crystal structures, properties, structure property relationships and several-important techniques (X-ray diffraction, thermal analysis and IR spectroscopy).