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Urease Inhibitiory Flavone Glucosides from Marrubium anisodon

Hussain A., Perveen S., Malik A., Afza N., Iqbal L., Tareen R. B.

Polish Journal of Chemistry

2009

Vol. 83, nr 7

1329-1335

Compounds 1–3, new flavonoid glucosides have been isolated from the ethyl acetate soluble fractions of Marrubium anisodon, along with apigenin 4'-O-beta-D-glucopyranoside 4, kaempferol 3-O-beta-D-glucopyranoside 5 and beta-sitosterol 3-O-beta-D-glucopyranoside 6, re - spectively. Their structures were as signed from 1H- and 13C-NMR spectra, DEPT and by COSY, HMQC, NOESY and HMBC experiments. Compounds 1–5 showed significant inhibitory activity against the enzyme urease.