Stilbene derivatives are widely distributed in the nature and they possess various bioactivities that includes antimicrobial, antifungal, antioxidant, hepato protective, anti-HIV, cytotoxic, anti-inflammatory and antiplatelet. We have synthesized novel derivatives of stilbenes by reacting various substituted phenyl acetic acid with aldehydes in presence of acetic anhydride and triethyl amine. These derivatives were characterised by various spectral techniques and were evaluated for their antimicrobial activities.
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Two stilbene derivatives have been synthesized in two step process. First step involved synthesis of acid derivative from p- chloro phenyl acetic acid, substituted benzaldehyde and triethyl amine, where as the second step involved synthesis of substituted stilbene derivatives (enoate or esters) through very simple route . These derivatives were characterized by various spectral techniques and were screened for their antimicrobial activities.
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