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The properties of fish skin collagen films after cross-linking with tannic acid

Sionkowska Alina, Lewandowska Katarzyna, Szulc Marta, Brudzyńska Patrycja, Kulka Karolina, Piwowarski Łukasz

Engineering of Biomaterials

2023

vol. 26, no. 168

9--14

Over the last three decades, an increasing interest in the preparation of new materials for wound healing has been observed. Collagen is a widely used biomaterial, and especially fish skin collagen is more and more popular among scientists. This study aimed to obtain thin films from native fish skin collagen and collagen cross-linked with tannic acid. Infrared spectroscopy, mechanical test, topographic imaging, and swelling test were used to characterize the features of the mentioned films. Statistical evaluation of the results was conducted with the Q-Dixon test. Infrared spectroscopy analysis showed that in the IR spectra of examined biomaterials, there are slight shifts in band positions after tannic acid cross-linking. The mechanical properties of the cross-linked material were different from those of the native collagen film. The Young’s modulus was higher for cross-linked collagen, whereas the elongation at break was lower than for pure collagen. The swelling of the collagen films increased after cross-linking with tannic acid. Swelling tests indicated that collagen cross-linked with tannic acid absorbs more water than before cross-linking. The properties of collagen films were significantly improved after tannic acid cross-linking. All alterations can be a result of collagen cross-linking by tannic acid, probably by forming hydrogen bonds between collagen and tannic acid.

Materials based on chitosan enriched with zinc nanoparticles for potential applications on the skin

Kulka Karolina, Szmejkowska Andżelika, Sionkowska Alina, Wypij Magdalena, Golińska Patrycja

Engineering of Biomaterials

2022

vol. 25, no. 167

24--31

Chitosan as a nontoxic, biodegradable, and biocompatible biopolymer with film-forming properties can also be modified to improve its parameters. Modification of polymer films by the addition of nanoparticles is an increasingly common solution due to the higher efficiency of products at the nanoscale compared to the macroscale. In this work, thin chitosan films enriched with biogenic zinc oxide nanoparticles (ZnONPs) from Fusarium solani IOR 825 were obtained by the solvent evaporation method. The influence of nanoadditive on the physicochemical, mechanical, and antimicrobial properties of the polymeric matrix was evaluated. Two different concentrations of ZnONPs were added to the chitosan solution. Spectrometric measurements, mechanical tests, microscopic imaging, and microbiological tests were performed for nanoparticlesmodified and control samples. Analysis revealed that ZnONPs influence the properties of chitosan films. FTIR spectroscopy showed changes that are the result of interactions between polymer matrix and the additive. Modified samples were characterized by increased values of Young’s modulus and tensile strength. SEM analysis combined with energy-dispersive X-ray spectrometry confirmed the presence of zinc in the modified films. The addition of nanoparticles slightly affected the surface morphology of the tested samples, and an increase in roughness was observed. Microbiological tests showed the biostatic activity of the films containing ZnONPs. The obtained films based on chitosan with the addition of ZnONPs can be considered easy-to-obtain biomaterials with potential use as cosmetic and biomedical products.