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1
Content available Physical properties of biodegradable polymers exposed to artificial plasma flow
Zegartowska Alicja, Stojko Mateusz, Joszko Kamil, Goldsztajn Karolina, Orłowska Ada, Szewczenko Janusz
Engineering of Biomaterials
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2023
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vol. 26, no. 170
9--13
EN
Despite significant advances in diagnosis and treatment, cardiovascular disease remains a major cause of premature death. Approximately 80% of cardiovascular incidents can be prevented by optimizing risk factor control and lifestyle modification, including dietary change. Treatment of cardiovascular disease, like treatment of other diseases, can be divided into conservative and curative. Conservative treatment is based on pharmacotherapy, while surgical treatment is mainly based on the use of PCI (percutaneous coronary intervention) procedures, i.e., increasing blood flow through narrowed arteries. This effect can be achieved with stents. The main limitation of metal stents is their permanent presence within the body, which can lead to complications such as thrombosis. A more advanced solution is the use of polymer or drug-coated stents, both of which are made of biodegradable materials. These stents are designed to release medications to support treatment and maintain their shape within the blood vessel before being naturally absorbed and eliminated by the body. In this study, the surface of stents made of polylactide was modified by applying a layer of PLGA using an ultrasound method. The study was carried out for uncoated and coated stents in both the initial state and after exposure to artificial plasma flow. The scope of the work included microscopic observations, weight measurements of the specimen, and examination of radial forces. The analysis of the results showed no clear effect of exposure on stent weight, but a clear effect of long- -term exposure on radial forces was observed.
2
Content available The technology for developing and obtaining the next generation of vascular stents through microinjection
Stojko Mateusz, Włodarczyk Jakub, Sobota Michał, Pastusiak Małgorzata, Jaworska Joanna, Musiał-Kulik Monika, Jelonek Katarzyna, Dobrzyński Piotr, Kasperczyk Janusz
Engineering of Biomaterials
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2021
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Vol. 24, no. 163
73
3
Content available Influence of crimping process on radial strength of vascular stent made of various bioresorbable polymers
Sobota Michał, Stojko Mateusz, Włodarczyk Jakub, Jelonek Katarzyna, Jaworska Joanna, Musiał-Kulik Monika, Pastusiak Małgorzata, Dobrzyński Piotr, Kasperczyk Janusz
Engineering of Biomaterials
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2021
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Vol. 24, no. 163
39
4
Content available Development of bioresorbable monofilament increasing the functionality of 3D printing technology in biomedical applications
Włodarczyk Jakub, Stojko Mateusz, Jelonek Katarzyna, Jaworska Joanna, Musiał-Kulik Monika, Pastusiak Małgorzata, Sobota Michał, Mikłowski Łukasz, Dobrzyński Piotr, Kasperczyk Janusz
Engineering of Biomaterials
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2021
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Vol. 24, no. 163
72
5
Content available Bioresorbable vascular scaffolds - effect of coating parameters on morphology and dose of antirestenotic drug
Jelonek Katarzyna, Jaworska Joanna, Musiał-Kulik Monika, Stojko Mateusz, Sobota Michał, Włodarczyk Jakub, Pastusiak Małgorzata, Szewczenko Janusz, Goldsztajn Karolina, Dobrzyński Piotr, Kasperczyk Janusz
Engineering of Biomaterials
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2021
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Vol. 24, no. 163
81
6
Content available Bioresorbable peripheral vascular stent with shape memory effect
Sobota Michał, Dobrzyński Piotr, Włodarczyk Jakub, Stojko Mateusz
Engineering of Biomaterials
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2019
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Vol. 22, no. 153 spec. iss.
60
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