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Parametrization of sub egmental infarcts using high spatial resolution 2DSTE and synthetic ultrasonic data

Żmigrodzki Jakub, Cygan Szymon, Kałużyński Krzysztof

Polish Journal of Medical Physics and Engineering

2023

Vol. 29, Iss. 4

195--207

Introduction: The purpose of this study was to assess the performance of a set of parameters in characterizing simulated infarcts in left ventricular (LV) models with variations in size and transmural extent. Material and methods: The deformation of the LV models with different infarct sizes was simulated using the Finite Element Method. These simulations provided meshes that were used to generate synthetic ultrasonic data within the FIELD II package. The strain components (longitudinal and circumferential) were then estimated over small subsegments of the of segments 7 and 12 (according to 17-segment left ventricle segmentation standard proposed by the American Heart Association - AHA17), using a hierarchical block matching method. The strain maps obtained were utilized to calculate the Strain Drop Factor (SDF) maps, which represent the percentage ratio of strain observed in the subsegments of the studied model to that observed in the healthy model. Infarct segmentation was performed using these maps, and various parameters were derived, including Infarct Cross-Section Area (ICSA), relative ICSA, Transmurality Ratio (TR), Mean Infarct Transmurality (MIT), strain drop factor in the infarcted region (SDFi), and Strain Contrast (SC). Results: The estimates of ICSA, SC, MIT, and SDFI showed good repeatability and demonstrated the ability to provide a quantitative assessment of the size and transmural extent of the infarcts. Conclusions: The study findings suggest that the evaluated parameters, including ICSA, SC, MIT, and SDFI, can be reliably used to assess the size and transmural extent of infarcts. These parameters offer a quantitative approach for characterizing infarcts based on strain analysis and have the potential to contribute to the diagnosis and evaluation of myocardial infarctions.

Comparison of three methods for reconstructing 3D motion from 2D video recordings for low cost gait analysis systems

Cygan Szymon, Specyalska Adriana

Polish Journal of Medical Physics and Engineering

2021

Vol. 27, Iss. 4

271--277

Purpose: The aim of this study was to quantify the accuracy of 3D trajectory reconstructions performed from two planar video recordings, using three different reconstruction methods. Additionally, the recordings were carried out using easily available equipment, like built-in cellphone cameras, making the methods suitable for low-cost applications. Methods: A setup for 3D motion tracking was constructed and used to acquire 2D video recordings subsequently used to reconstruct the 3D trajectories by 1) merging appropriate coordinates, 2) merging coordinates with proportional scaling, and 3) calculating the 3D position based on markers’ projections on the viewing plane. As experimental verification, two markers moving at a fixed distance of 98.9 cm were used to assess the consistency of results. Next, gait analysis in five volunteers was carried out to quantify the differences resulting from different reconstruction methods. Results: Quantitative evaluation of the investigated 3D trajectories reconstruction methods showed significant differences between those methods, with the worst reconstruction approach resulting in a maximum error of 50% (standard deviation 13%), while the best resulting in a maximum error of 1% (standard deviation 0.44%). The gait analysis results showed differences in mean angles obtained with each reconstruction method reaching only 2°, which can be attributed to the limited measurement volume. Conclusions: Reconstructing 3D trajectory from 2D views without accounting for the “perspective error” results in significant reconstruction errors. The third method described in this study enables a significant reduction of this issue. Combined with the proposed setup, it provides a functional, low-cost gait analysis system.