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Chitosan-based films with selected moisturizing additives

Kaczmarek-Szczepańska Beata, Glajc Patrycja, Zasada Lidia

Engineering of Biomaterials

2025

vol. 28, no. 173

art. no. 9

This study presents the development and characterization of thin films based on chitosan, modified with selected moisturizing additives, including hyaluronic acid, snail mucus extract, natural moisturizing factor (NMF), and gluconolactone, chosen for their common application in skin care products. Chitosan was dissolved in 0.1 M acetic acid to prepare a 1% w/v solution, and each additive was incorporated at 10% w/w relative to the chitosan content, both individually and in combination. The resulting mixtures were cast and dried under ambient conditions to form flexible films. Comprehensive characterization was performed using Fourier Transform Infrared Spectroscopy (FTIR), atomic force microscopy (AFM), contact angle measurements, and mechanical testing. The results revealed significant differences in chemical interactions, surface morphology, wettability, and mechanical behavior depending on the additive used. Notably, the formulation combining all moisturizing agents exhibited the most favorable balance of mechanical strength, flexibility, and hydration-related surface characteristics. FTIR spectra indicated molecular-level interactions between chitosan and the additives, particularly through hydrogen bonding. AFM analysis showed variations in surface roughness, while contact angle measurements highlighted changes in surface energy and hydrophilicity. These findings indicate that the modified chitosan films are promising candidates for innovative, sustainable dermatological and cosmetic applications, especially for effective skin hydration and use in skin care products.

Preparation and comprehensive characterization of chitosan-based films enhanced with ferulic acid

Zasada Lidia, Chmielniak Dorota, Gwizdalska Klaudia, Kaczmarek-Szczepańska Beata

Engineering of Biomaterials

2024

vol. 27, no. 172

art. no. 08

This study explores the development and detailed characterization of chitosan-based films enhanced with ferulic acid to improve their properties for biomedical, environmental, and packaging applications. Chitosan, a biopolymer derived from chitin, exhibits valuable attributes such as biocompatibility, biodegradability, and antimicrobial properties. However, it requires modifications to overcome limitations in mechanical strength, water permeability, and antioxidant properties. Ferulic acid, a phenolic compound, was incorporated into chitosan films at varying concentrations (1%, 2%, 5%, and 10%) to investigate its influence on film properties. The films were characterized through FTIR to confirm interactions between ferulic acid and chitosan, resulting in enhanced mechanical flexibility, thermal stability, and water resistance. Mechanical tests indicated that ferulic acid improved film flexibility while maintaining tensile strength, making it suitable for flexible packaging and wound dressings. Additionally, water vapour permeability and swelling tests suggested potential improvements in moisture control. Optical assessments showed increased whiteness and reduced colour variability, highlighting the aesthetic and protective advantages of ferulic acid-enriched films. These findings suggest that ferulic acid-modified chitosan films can serve as multifunctional biomaterials, addressing the growing demand for sustainable, high-performance materials in various industries. Further research on biological properties is recommended to fully establish their applicability in biomedicine and environmentally sensitive applications.