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Influence of bioactive metal fillers on antimicrobial properties of PA12 composites produced by laser-based Powder Bed Fusion of Polymers

Gruber Piotr, Szymczyk-Ziolkowska Patrycja, Olejarczyk Michał, Junka Adam, Fabianowska-Majewska Krystyna, Brozyna Malwina, Kurzynowski Tomasz

Acta of Bioengineering and Biomechanics

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2023

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Vol. 25, no. 4

EN

This study investigated the influence of three types of metallic microfillers, spherical silver and spherical, and dendritic copper, on the ability of polyamide 12 (PA12) to inhibit microorganism growth on the surfaces of samples produced using laser-based powder bed fusion of polymers (PBF-LB/P). The aim of this study was to initially characterize these materials regarding their potential applicability for parts dedicated to use in the hospitals, which surfaces are periodically disinfected using chemical and/or physical measures.

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Influence of the different composites (PLA/PLLA/HA/β-TCP) contents manufactured with the use of additive laser technology on the biocompatibility

Woźna Anna E., Junka Adam, Hoppe Viktoria W.

Acta of Bioengineering and Biomechanics

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2021

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Vol. 23, no. 2

169--180

EN

Purpose: In recent years, it has become extremely important to search for more and more natural and biocompatible materials that allow for the reconstruction of natural tissues with as few side effects as possible. The aim of the present paper is to define mechanical properties such as compressive stress and Young’s Modulus and to estimate the ability of human bone cell strains to form biofilm on bioresorbable composites manufactured of polylactide and poly-l-lactide (PLA and PLLA) and hydroxyapatite and tricalcium phosphate (HA and β-TCP) with the use of Selective Laser Sintering (SLS) method. Methods: Microbiological tests were conducted on three variants of solid specimen made with additive laser technology. Samples with different chemical compositions were made with appropriate manufacturing parameters ensuring stability of both composite ingredients. Microbiological in vitro tests helped to determine cytotoxicity of specific samples toward bone cells. Results: The results obtained indicate significantly increased ability of osteoblasts to form colonies on the surface of materials with higher content of hydroxyapatite ceramics compared to surfaces of lower hydroxyapatite content. Conclusions: The data provided can be useful for future applications of the SLS technology in production of bioresorbable PLA/PLLA/HA/β-TCP medical implants.

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Biological evaluation of selective laser melted magnesium alloy powder

Pawlak Andrzej P., Szymczyk-Ziółkowska Patrycja E., Junka Adam, Chlebus Edward

Acta of Bioengineering and Biomechanics

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2021

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Vol. 23, no. 1

121--133

EN

Purpose: The current study examined magnesium alloy AZ31B specimens manufactured with Additive Manufacturing method (selective laser melting – SLM) to investigate the applicability of this technology for the production of medical devices. Methods: Osteoblast cells and bacterial biofilm growth ability on specimen was examined and the effect of surface state on corrosion resistance was evaluated by electrochemical and immersion methods. Results: High survival of hFOB cells, as well as a strong tendency for Pseudomonas aeruginosa and Staphylococcus aureus biofilm proliferation on the surface of the tested specimens were shown. SLM-processed AZ31B alloy has a higher corrosion resistance in 0.9% NaCl solution and in a multi-electrolyte saline solution than the material in a conventional form of a rolled sheet. Conclusions: It has been demonstrated that the strong development of the surface of as-built processed specimens results in a significantly increased corrosion rate, which hinders the production of complex structures in tissue engineering products that support cell ingrowth.