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Monitoring and control of a class of distributed parameter bioreactors with application of the substrate consumption rate

Czeczot J., Metzger M., Babary J. P., Nihtilä M.

Archives of Control Sciences

2001

Vol. 11, no. 1/2

5-22

This paper deals with the idea of estimation of the substrate consumption rate at each point of the tube of the classical distributed parameter bioreactor and with its application to the monitoring and control of this system. It is shown how to approximate the profile of this parameter on the basis of the orthogonal collocation method and of the recursive least-squares procedure with adjustable forgetting factor. Then, it is suggested how to apply this profile for monitoring of the bioreactor work (calculation of the current mass flux of the substrate being reacted in the reactor tube and of the total mass of the substrate converted in the bioreactor during its activity). Finally, the linearizing adaptive control law is derived on the basis of the substrate consumption rate estimated at the outlet of the bioreactor. This controller allows the outlet substrate concentration to be kept at its desired value by manipulating the velocity of the flowing medium. The idea presented in this paper has been validated by means of the computer simulation and the results, proving its very good properties, complete the paper.