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1 Ecological Chemistry and Engineering. S

1 2022

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The impact of propanol, n-butanol and pentanol on aqueous dispersions of sonicated liposomes. EPR study

Bartnikowska Agnieszka, Pytel Barbara, Man Dariusz

Ecological Chemistry and Engineering. S

2022

Vol. 29, nr 4

565--579

This paper presents the effect of selected alcohols on the fluidity of liposome membranes obtained in sonication of DPPC lecithin. Using the EPR technique, the duality of propanol, n-butanol and pentanol on the behaviour of the aqueous dispersion of liposomes was demonstrated. It was shown that after exceeding a certain concentration, these alcohols initiate dispersion foaming, leading to phase separation: liposome dispersion - lipid foam. The influence of the shape of the molecule and the length of hydrocarbon chains on the effectiveness of destabilisation of the structure of lipid membranes was indicated.