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Application of the substrate consumption rate to the monitoring of distributed parameter bioreactors

Czeczot J., Metzger M., Babary J., Nihtilae M.

Control and Cybernetics

2001

Vol. 30, no 1

81-98

This paper deals with the idea of estimation of the substrate consumption rate at each point of the tube of the classical distributed parameter bioreactor and its application to the monitoring of this system. It is shown how to approximate the profile of this parameter on the basis of the orthogonal collocation method and the recursive least-squares procedure with adjustable forgetting factor. Then, it is suggested how to apply this profile for monitoring of the bioreactor work (calculation of the current mass flux of the substrate being reacted in the reactor tube and of the total mass of the substrate reacted in the bioreactor tube during its activity). The idea presented in this paper ivas validated by means of the computer simulation and the results proving its very good performance complete the paper.