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The Design of RNA Biosensor Based on Nano-gold and Magnetic Nano-particle

Yang Jing, Yin Zhi-xiang, Cui Jian-zhong, Huang Kai-feng

Fundamenta Informaticae

2019

Vol. 164, nr 2-3

289--298

Detecting the quality of drinking water is very important in researching the current status and predicting trends of variation, as well as fundamentally solving the water pollution problem. Recently, the application and development of biosensor provide a powerful analytical tool for detecting pollutants of drinking water, but high selectivity, specificity, short response time, and low cost are particularly desired in the detection process. In this paper, RNA molecules in combination with nano-gold and magnetic nano-particles were proposed as design strategies of the biosensor. The proposed designs have distinct advantages over conventional biosensor in the following aspects: the high affinity capacity, sensitivity, and practicability. Our work provided an alternative method to monitor the environment of drinking water, and may find applications in various monitoring fields.