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Automated diagnosis of depression from EEG signals using traditional and deep learning approaches: A comparative analysis

Khosla Ashima, Khandnor Padmavati, Chand Trilok

Biocybernetics and Biomedical Engineering

2022

Vol. 42, no. 1

108--142

Depression is one of the significant contributors to the global burden disease, affecting nearly 264 million people worldwide along with the increasing rate of suicidal deaths. Electroencephalogram (EEG), a non-invasive functional neuroimaging tool has been widely used to study the significant biomarkers for the diagnosis of the disorder. Computational Psychiatry is a novel avenue of research that has shown a tremendous success in the automated diagnosis of depression. The present comprehensive review concentrate on two approaches widely adopted for an EEG based automated diagnosis of depression: Deep Learning (DL) approach and the traditional approach based upon Machine Learning (ML). In this review, we focus on performing the comparative analysis of a variety of signal processing and classification methods adopted in the existing literature for these approaches. We have discussed a variety of EEG based objective biomarkers and the data acquisition systems adopted for the diagnosis of depression. Few EEG studies focusing on multimodal fusion of data have also been explained. Additionally, the research based upon the analysis and prediction of treatment outcome response for depression using EEG signals and machine learning techniques has been briefly discussed to aware the researchers about this emerging field. Finally, the future opportunities and a valuable discussion on major issues related to this field have been summarized that will help the researchers in developing more reliable and computationally intelligent systems in the field of psychiatry.

A comparative analysis of signal processing and classification methods for different applications based on EEG signals

Khosla Ashima, Khandnor Padmavati, Chand Trilok

Biocybernetics and Biomedical Engineering

2020

Vol. 40, no. 2

649--690

Electroencephalogram (EEG) measures the neuronal activities in the form of electric currents that are generated due to the synchronized activity by a group of specialized pyramidal cells inside the brain. The study presents a brief comparison of various functional neuroimaging techniques, revealing the excellent neuroimaging capabilities of EEG signals such as high temporal resolution, inexpensiveness, portability, and non-invasiveness as compared to the other techniques such as positron emission tomography, magnetoencephalogram, func-tional magnetic resonance imaging, and transcranial magnetic stimulation. Different types of frequency bands associated with the brain signals are also being summarized. The main purpose of this literature survey is to cover the maximum possible applications of EEG signals based on computer-aided technologies, ranging from the diagnosis of various neurological disorders such as epilepsy, major depressive disorder, alcohol use disorder, and dementia to the monitoring of other applications such as motor imagery, identity authentication, emotion recognition, sleep stage classification, eye state detection, and drowsiness monitoring. After reviewing them, the comparative analysis of the publicly available EEG datasets and other local data acquisition methods, preprocessing techniques, feature extraction methods, and the result analysis through the classification models and statistical tests has been presented. Then the research gaps and future directions in the present studies have been summarized with the aim to inspire the readers to explore more opportunities on the current topic. Finally, the survey has been completed with the brief description about the studies exploring the fusion of brain signals from multiple modalities.