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PL
Opisano aparaturę i oprogramowanie przeznaczone do badań czynnościowych fMRI, opracowane w ramach realizacji projektu badawczego Ministerstwa Nauki i Szkolnictwa Wyższego oraz prac inżynierskich i magisterskich studentów Wydziału Elektroniki i Technik Informacyjnych (specjalność Elektronika i Informatyka w Medycynie).
EN
This paper describes software and hardware tools designed for brain studies with the aid of functional Magnetic Resonance Imaging (fMRI). Presented work was supported by the grant from Polish Science and Education Ministry and realized during Master's degree courses at the Faculty of Electronics and Information Technology (specialization: electronics and informatics in medicine).
EN
For patients with pharmacoresistant epilepsy only surgieal intervention is an effeetive solution. To prevent unnecessary damage of important regions of the brain, there is a need for mapping of funetional organization of cerebral cortex. In cIinical practiec together with neuropsyehological evaluation an invasive techniques are used: intraoperative cortex mapping using electrieal stimulation and Wada test. In this work, usefulness of fMRI in preoperative planning for those patients was assessed. In cooperation with group of neuropsyehologists five patients were studied. A group of tests was prepared eonsisting of phonetie and semantic fIueney for Broea mapping and a group of motoric tests. All experiments were performed on two seanners for repeatability assessment. For each patient individual maps of active regions were eaculated using SPM2 package and self made tools. For verification of results cIinical evaluation methods were used: Wada test comparison, comparison with intraoperative stimulation and spatial relations between lesions and functional regions. Three of five patients had surgical intervention. None of them presented any degradation in most endangered function - verbal for 2 patients and motoric in one case. All patients will be examined after 6 months. At current stage of study a cIinical protocol is being designed for routine use.
PL
W niniejszym artykule przedstawiono metodę tworzenia obrazu czynnościowego z serii czasowej obrazów tomograficznych (CT, MRI). Obraz parametryczny wyliczany jest za pomocą modelu otrzymanego z referencyjnego obszaru mózgu z zastosowaniem analizy korelacyjnej. Przyjęcie takiego sposobu postępowania umożliwia wyeliminowanie najbardziej zawodnego i czasochłonnego etapu tworzenia obrazu czynnościowego, jakim jest procedura aproksymacyjna.
EN
Parametric images can be obtained from CT or MRI modalities through a special sequential scanning after the injection of a contrast medium. This kind of examination, called dynamic study, forms an image sequence that monitors the first pass transit of injected boluses of the contrast agents, through an organ of interest. The new proposed method applies correlation and discrimination analysis to each concentration-time curve instead of fitting them to any a priori and arbitrary tracer kinetic model. We have previously shown that temporal correlation methods can be used to analyse functional images of the brain, kidney and heart (Bogorodzki, 1996, Lo 1996).
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