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Bionanomaterials – an emerging field of nanotechnology

Shelin A. R., Meenakshi S.

Archives of Materials Science and Engineering

2023

Vol. 121, nr 1

33--41

Purpose: The science that involves nano-sized particles have been shown to have a huge impact on a variety of research fields, such as electronics, medicine, engineering, robotics and technology. The involvement of biological agents in nanoscience helped in the origin of bionanotechnology, which is deeply rooted in therapeutic and medical applications. This review provides an initiative to understand the combination of biological molecules and nanoparticles in delivering a great impression in the world of therapeutics. Design/methodology/approach: Conjugation of nanoparticles with the biological molecules makes them more friendly for the living system by increasing biocompatibility and reducing toxicity. Findings: Growing research in this area has revealed the identification and characterization of numerous biological agents of nano-sized that can serve as better carrier systems. They are exploited in the development of advanced nanoparticle-based targeted drug delivery systems. In general, either the combined form or the one in the derived form of nanoparticles from different biological organisms provides a valuable understanding of their specifications and importance in different therapeutic aspects. Research limitations/implications: The combined form of biological molecules and nanoparticles is not yet well understood, and this might provide a baseline for prospects. Originality/value: This review provides an understanding of biologically synthesized and conjugated nanoparticles and their potential as therapeutic norms and highlights their applications, especially in the clinical field.

An epitome on encapsulation of probiotics

Ramadevi S., Meenakshi S.

Archives of Materials Science and Engineering

2022

Vol. 116, nr 1

34--41

Purpose: Nanotechnology is one of the highly evolving fields of research having immense potential in various fields of healthcare sectors. The very advent of nanotechnology lies in its ability to serve as a targeted drug delivery system. The introduction of a new branch namely bionanotechnology has further expanded the scope, especially in the diagnostics and treatment of various diseases. Probiotics being a natural source with a plethora of beneficial properties have been investigated actively in recent days. Probiotics administered into the digestive system have been shown to promote gut health by increasing the microbial balance in the gut. However, the bioavailability of such administered probiotics remains a major concern. These probiotics are protected through microencapsulation techniques, which encapsulate them in small capsules. Several nanoparticles with varied dimensions, forms, surfaces and composites have recently been investigated for probiotic microencapsulation. This has been used for various therapeutic applications, such as drug delivery. This review gives an insight on various materials and strategies used for probiotic encapsulation. Design/methodology/approach: The main aim of this review is to give a perception of the different types of methods of probiotic encapsulation. Findings: This review implies the significance of probiotics and subsequent active release in the gastrointestinal system. Different sections of this review paper, on the other hand, may offer up new opportunities for comprehensive research in the field of microencapsulation for boosting probiotic viability and also talks about the various encapsulating materials that has been employed. Originality/value: This review emphasizes more perceptions about the ongoing and imminent techniques for encapsulating probiotics.