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1

Models Based on Mechanical Properties of Biological Cells in Microfluidics

Lizanets D., Lobur M., Matviykiv O.

Machine Dynamics Research

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2015

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Vol. 39, No. 3

127-135

EN

The paper is devoted to the modeling deformation of biological cell in microfluidic microchannel devices. The background and purpos of actual research is developing mechanical model of the biological cell shell for improving simulation and design of microfluidic lab-chip diagnostic devices.

2

Mesoscale Modeling of Complex Microfluidic Flows

Matviykiv O.

ECONTECHMOD : An International Quarterly Journal on Economics of Technology and Modelling Processes

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2015

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Vol. 4, No 1

77--85

EN

The mesoscale description of multiphase flow in a typical Lab-chip diagnostic device is presented in actual article. The mesoscopic lattice Boltzmann method, which involve evolution equations for the single particle distribution function, was applied for the modeling of complex microfluidic flows. The general D2Q9 lattice Boltzmann formulation, considered multiphase flows, was developed. Three types of boundary conditions were used for the mesoscopic modeling: “ghost-fluid”, “bounce-back” and “periodic boundaries”. Traditional Dirichlet and Neumann macroscopic boundary conditions were transformed into mesoscopic lattice formulations. Algorithm of fluid flow solution, based on BGK single-relaxation-time scheme was proposed and implemented. The scaling procedure was used for physical parameters convertion into non-dimensional units. Simulation procedure was tested on a fluid flow with single solid particle. The final results showed good consistence with fundamental flow phenomena.

3

Multiphase Flow Models for Applications in Microfluidic Mechanics

Matviykiv O., Dmytryshyn B., Faitas O.

Machine Dynamics Research

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2013

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Vol. 37, No. 2

71-75

EN

The importance of interaction between mechanical CAD workflow and fluid-flow CAE simulations in modern micromachinery design projects are investigated. Fluid flow models for simulating multiphase and multicomponent microfluidic flows were analyzed and presented.

4

Collaborative Framework for Multiscale Design of mkFluidic BioMEMS

Matviykiv O.

Machine Dynamics Research

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2013

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Vol. 37, No. 3

53-60

EN

Engineering design of pure multidisciplinary and multiscale devices, like bioMEMS is still a challenge, even with modern CAD/CAE tools, because of the necessity of deep expertise knowledge in all multiphysics domains. Actual research propose an structure of heterogeneous collaborative design platform for the computer-aided support of multiscale simulation and design process. A prototype of collaborative framework was developed.