This study investigated the relationship between the parameters of the DLP manufacturing process and the structure of photopolymerizable acrylic resins. Four different process parameters were established to produce different thin-walled acrylic sample series: exposure time, layer thickness, area offset, and number of transition layers. The structure and the surface of the obtained samples were examined with the use of the FTIR–ATR method and an optical microscope, respectively. It was proved that extension of the exposure time increases the density of crosslinking and sample thickness. A decreasing crosslinking density due to rising layer thickness is observed. The area offset affects only the dimensions of the sample, predictably reducing the dimensions of the sample as the compensation increases. The absence of transition layers proved unfavorable in many respects, both structurally and geometrically.
Additive manufacturing is a technology that can be successfully used in pharmacy and medicine. One of the examples of products that can be additively manufactured are microneedle systems. The specificity of these products, which are used for transdermal drug delivery, makes additive manufacturing a perfect choice for related research. However, the dimensions of microneedles usually do not exceed 2 mm, which means that manufacturing them using the most widely available additive manufacturing method, Fused Deposition Modelling (FDM), is problematic. In this study, the authors decided to investigate the possibilities of manufacturing microneedle systems using the FDM method in such a way as to minimize or exclude the need for post-processing. Five types of microneedle geometries were tested in four sizes, examining how changing the values of FDM process parameters would affect the accuracy of reproducing the digital geometry of the microneedles. From the point of view of the application of microneedle systems, it is not only necessary to obtain the designed shape of the microneedles, but also to maintain their appropriate strength. The study presents the results of the bending and compression strength of microneedles made of polylactic acid.
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